From in vitro cell cultures to human iPSC-derived neurons and human-derived stem cells, explore new pathways in drug discovery and brain research
The high resolution CMOS-MEA technology featured in BioCAM X can foster your R&D on neuronal networks in brain organoids, tissues and slices by enabling you to:
Our high-density microelectrode array (HD-MEA) is the ideal tool in pre-clinical toxicological/pharmacological screenings to assess in vitro models of severe long term neurodegenerative diseases, such as Alzheimer's and Parkinson's.
A high number of electrophysiological activity recording sites facilitates the evaluation of, functional alteration caused by insulting agents, such as AÎ² oligomers, and the rescue effects of neuroprotective compounds. Label-free assays offer unprecedented statistical significance and a sensitivity superior to most common cellular death assays or imaging techniques, as demonstrated in Amin et al., Sci Reports 2017.
Human-induced pluripotent stem cell-derived neuronal networks are the most promising tools to improve the understanding of brain disease through in vitro modeling. Our high-density microelectrode arrays, or multielectrode arrays (HD-MEAs), are the first CMOS-based devices fully validated with human-derived neurons. Spontaneous, as well as electrically-evoked, electrophysiological activity has been monitored for more than three months over different adhesion coatings. See more
Functional connectivity in neuronal assemblies is a hot topic for neuroscientists. Our high-density microelectrode array, also known as a multielectrode array (HD-MEA), allows the detailed study of interconnected neuronal networks. See more
Combined with optical imaging, our HD-MEA is a powerful tool to investigate the relationship between function and structure in in vitro cell cultures. See more