OUR MISSION

We strive to provide researchers with breakthrough technology to improve the understanding of organs such as the brain and heart and their related illnesses.

TECHNOLOGY

Microelectrode arrays (MEA) meet CMOS technology

Our disruptive microelectrode array, also known as multielectrode array (MEA), technology revolutionizes brain research by enabling a deeper investigation of neuronal networks. Our pioneering work with CMOS technology has allowed researchers to visualize signal propagations between thousands of cells at a sub-millisecond scale for the first time.

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APPLICATIONS

Extend your possibilities in drug discovery and brain research

By collecting high-resolution electrophysiological data from neurons, cardiac cells, brain organoids, and human-derived stem cells, our microelectrode array (multielectrode array) technology opens up new possibilities in drug discovery by enabling functional imaging assays, the identification of network functional and dysfunctional states and the precise evaluation of pharmacological responses.

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PRODUCTS

High-resolution electrophysiology platforms

Explore our full line of microelectrode arrays, also known as multielectrode arrays (MEAs), our solution to your experimental needs.

BioCAM X

Discover a new dimension with high-resolution in vitro electrophysiology

Stemming from more than 10 years of development, our high-resolution CMOS-MEA system combines the latest integrated circuit computing performance with a durable and compact design.

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HD-MEA Probes

Unleash the power of your neuronal preparations

High density microelectrode arrays (HD-MEAs) featuring 4096 simultaneous readout channels and 16 stimulation sites arranged in different configurations meeting various experimental needs.

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Accessories

Take your research further with customized accessories

Designed to fit our HD-MEA platforms, our accessories take your research in drug discovery, brain organoids, neuronal networks, and human-derived stem cells to the next level.

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BrainWave

Gathering high-resolution electrophysiological data has never been easier

Our advanced acquisition and analysis software is designed to manage dense electrophysiological data sets. BrainWave facilitates real-time visualization and the extraction of key metrics from high-density microelectrode array, or multielectrode array (HD-MEA), chips.

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RESOURCES

See our microelectrode array technology in action

Explore the capabilities of our high-density microelectrode arrays, also known as multielectrode arrays (HD-MEAs), and software tools by taking a look at these experimental examples and downloading the latest version of BrainWave.

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Latest publications

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dissociated cultures

State-dependent representation of stimulus-evoked activity in high-density recordings of neural culturespaper

Nieus T., D’Andrea V., Amin H., Di Marco S., Safaai H., Maccione A., Berdondini L. and Panzeri S.

Scientific Reports vol 8, Article number: 5578 (2018), doi:10.1038/s41598-018-23853-x

acute brain slices

High Density Multi Electrode Array: a new tool to monitor seizure-like activity evoked by different convulsant drugsconf. proc.

Sessolo M., Ugolini A., Maccione A., Gandolfo M., Corsi M., Virginio C.

SFN 2018 (San Diego)

acute retina

Non-parametric Physiological Classification of Retinal Ganglion Cells in the Mouse Retinapaper

Jouty J., Hilgen G., Sernagor E. and Hennig M.H.

Front. Cell. Neurosci. (2018) doi:https://doi.org/10.3389/fncel.2018.00481

News

Feb 18 2019

Stem Cells and Organoids in Development and Disease Symposium

We will be at the Stem Cells & Organoids in Development & Disease Symposium in Amsterdam on February 20-22. Meet us at booth #50 to see how our cutting-edge microelectrode array technology boosts research on organoids and stem cells. 

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Feb 15 2019

Meet 3Brain at the Roadshow in Paris

We're bringing our advanced microelectrode array technology to the City of Lights this February 18th and 19th. Our Roadshow in Paris is an incredible opportunity to discover BioCAM X, our MEA probes and latest BrainWave 4 software and see how they meet your research needs. To find out more, send an email to info@3brain.com.

Jan 03 2019

BrainWave 4 is 3Brain's newest software for HD electrophysiological data

BrainWave 4 offers a new way to collect, analyze and export electrophysiological data gathered using 3Brain's microelectrode array (MEA) platforms. With this feature-rich software, you can filter the data, detect and sort spikes in activity, analyze local field potentials (LPFs), and much more. Find out how you can download BrainWave 4 and choose the right license to advance your research in drug discovery, brain organoids, neuronal networks and the retina.

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Oct 26 2018

Project Khíron: High-density multi electrode array goes 3D

A new gold standard for electrical measurement in the emerging in vitro world of three dimensional models. That's what Swiss medtech 3Brain has established by partnering with CSEM. Its Khíron chip enables fast, accurate intra-tissue measurement and continuous nutrient and oxygen supply through all tissue layers for the first time. And it is set to unlock the potential of next-generation cell culture models in disease modeling and preclinical studies.

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