Publications

Neuronal Cultures

Alteration of neural network and hippocampal slice activation through exosomes derived from 5XFAD nasal lavage fluid

Alteration of neural network and hippocampal slice activation through exosomes derived from 5XFAD nasal lavage fluid

(paper)

Kim S., Jeon J., Ganbat D., Kim T., Shin K., Hong S. and Hong J.

Int. J. Mol. Sci. (2023) DOI: 10.3390/ijms241814064

Acute Retina

Birds multiplex spectral and temporal visual information via retinal On- and Off-channels

Birds multiplex spectral and temporal visual information via retinal On- and Off-channels

(paper)

Seifert M., A. Roberts P., Kafetzis G., Osorio D. and Baden T.

Nature Communications (2023). DOI: 10.1038/s41467-023-41032-z

Acute Brain Slices

Anisotropy and Frequency Dependence of Signal Propagation in the Cerebellar Circuit Revealed by High-Density Multielectrode Array Recordings

Anisotropy and Frequency Dependence of Signal Propagation in the Cerebellar Circuit Revealed by High-Density Multielectrode Array Recordings

Monteverdi A., Di Domenico D., D’Angelo E., Mapelli L.

Biomedicines (2023). DOI: 10.3390/biomedicines11051475

Acute Brain Slices

Proinflammatory activation of microglia in the cerebellum hyperexcites Purkinje cells to trigger ataxia

Proinflammatory activation of microglia in the cerebellum hyperexcites Purkinje cells to trigger ataxia

(paper)

Xie S-T., Fan W-C., Zhao X-S., Ma X-Y., Li Z-L., Zhao Y-R., Yang F., Shi Y., Rong H., Cui Z-S., Chen J-Y., Li H-Z., Yan C., Zhang O., Wang J-J., Zhang X-Y., Gu X-P., Ma Z-L. and Zhu J-N.

Pharmacological Research (2023). DOI: 10.1016/j.phrs.2023.106773

Organoids

Human-derived cortical neurospheroids coupled to passive, high-density and 3D MEAs: a valid platform for functional tests

Human-derived cortical neurospheroids coupled to passive, high-density and 3D MEAs: a valid platform for functional tests

(paper)

Muzzi L., Di Lisa D., Falappa M., Pepe S., Maccione A., Pastorino L., Martinoia S. and Frega M.

Bioengineering (2023) DOI: 10.3390/bioengineering10040449

Neuronal Cultures

Exploring the Pathological Effect of Aβ42 Oligomers on Neural Networks in Primary Cortical Neuron Culture

Exploring the Pathological Effect of Aβ42 Oligomers on Neural Networks in Primary Cortical Neuron Culture

(paper)

Ganbat D., Kyong Jeon J. and Lee Y.

Int. J. Mol. Sci. (2023) DOI: 10.3390/ijms24076641

Neuronal Cultures

Neuronal network activity and connectivity are impaired in a conditional knockout mouse model with PCDH19 mosaic expression

Neuronal network activity and connectivity are impaired in a conditional knockout mouse model with PCDH19 mosaic expression

(paper)

Giansante G., Mazzoleni S., G. Zippo A., Ponzoni L. Ghilardi A., Maiellano G., Lewerissa E., van Hugte E., Nadif Kasri N., Francolini M., Sala M., Murru L., Bassani S. and Passafaro M.

Mol Psychiatry (2023). DOI: 10.1038/s41380-023-02022-1

Acute Brain Slices

A deep generative adversarial network capturing complex spiral waves in disinhibited circuits of the cerebral cortex

A deep generative adversarial network capturing complex spiral waves in disinhibited circuits of the cerebral cortex

(paper)

Boucher-Routhier M. and Thivierge JP.

BMC Neuorscience (2023) DOI: 10.1186/s12868-023-00792-6

Acute Brain Slices

Lipid-accumulated reactive astrocytes promote disease progression in epilepsy

Lipid-accumulated reactive astrocytes promote disease progression in epilepsy

Chen Z-P., Wang S., Zhao X., Fang W., Wang Z., Ye H., Wang M-J., Ke L., Huang T., Lv L., Jiang X., Zhang Q.,Li L., Xie S-T., Zhu Y-N., Hang C., Chen D., Liu X., Yan C.

Nature Neuroscience (2023). DOI: 10.1038/s41593-023-01288-6

Organoids

Incorporating microglia-like cells in human induced pluripotent stem cell-derived retinal organoids

Incorporating microglia-like cells in human induced pluripotent stem cell-derived retinal organoids

(paper)

Chichagova V., Georgiou M., Carter M., Dorgau B., Hilgen G., Collin J., Queen R., Chung G., Ajeian J., Moya-Molina M., Kustermann S., Pognan F., Hewitt P., Schmitt M., Sernagor E., Armstrong L. and Lako M.

Journal of Cellular and Molecular Medicine (2023). DOI: 10.1111/jcmm.17670

Acute Retina

Glial Bmal1 role in mammalian retina daily changes

Glial Bmal1 role in mammalian retina daily changes

(paper)

Riccitelli S., Boi F., Lonardoni D., Giantomasi L., Barca-Mayo O., De Pietri Tonelli D., Bisti S., Di Marco S. and Berdondini L.

Scientific Reports (2022). DOI: 10.1038/s41598-022-25783-1

Acute Brain Slices

Large-scale Multimodal Recordings on a High-density Neurochip: Olfactory Bulb and Hippocampal Networks

Large-scale Multimodal Recordings on a High-density Neurochip: Olfactory Bulb and Hippocampal Networks

Emery B. A., Hu X., Muageri L., Khanzada S., Klutsch D., Altuntac E., Amin H

IEEE Engineering in Medicine & Biology Society (EMBC), (2022) DOI:10.1109/EMBC48229.2022.9871961

Acute Brain Slices

Xenon LFP Analysis Platform Is a Novel Graphical User Interface for Analysis of Local Field Potential From Large-Scale MEA Recordings

Xenon LFP Analysis Platform Is a Novel Graphical User Interface for Analysis of Local Field Potential From Large-Scale MEA Recordings

(paper)

Mahadevan A., Codadu N.K. and Parrish R.R.

Frontiers in Neuroscience (2022). DOI: 10.3389/fnins.2022.904931

Acute Brain Slices

Modified climbing fiber/Purkinje cell synaptic connectivity in the cerebellum of the neonatal phencyclidine model of schizophrenia

Modified climbing fiber/Purkinje cell synaptic connectivity in the cerebellum of the neonatal phencyclidine model of schizophrenia

(paper)

Veleanu M., Urrieta-Chávez B., Sigoillot S. M., and Selimi F.

PNAS (2022). DOI: 10.1073/pnas.2122544119

Acute Retina

Receptive field estimation in large visual neuron assemblies using a super-resolution approach

Receptive field estimation in large visual neuron assemblies using a super-resolution approach

(paper)

Pamplona D., Hilgen G., Hennig M.H., Cessac B., Sernagor E., and Kornprobst P.

Journal of Neurophysiology (2022). DOI: 10.1152/jn.00076.2021

Neuronal Cultures

Revealing directed effective connectivity of cortical neuronal networks from measurements

Revealing directed effective connectivity of cortical neuronal networks from measurements

(paper)

Sun C., Lin K.C., Yeung Y., Ching E.S.C., Huang Y., Lai P., and Chan C.K.

APS Physics (2022). DOI: 10.1103/PhysRevE.105.044406

Acute Brain Slices

Hypoxia induced carbonic anhydrase mediated dorsal horn neuron activation and induction of neuropathic pain

Hypoxia induced carbonic anhydrase mediated dorsal horn neuron activation and induction of neuropathic pain

(paper)

Lobo M.E.D.V., Weir N., Hardowar L., Al Ojaimi Y., Madden R., Gibson A., Bestall S.M., Hirashima M., Schaffer C.B., Donaldson L.F., Bates D.O. and Hulse R.H.

PAIN (2022). DOI: 10.1097/j.pain.0000000000002627

Acute Brain Slices

Discovering Microcircuit Secrets With Multi-Spot Imaging and Electrophysiological Recordings: The Example of Cerebellar Network Dynamics

Discovering Microcircuit Secrets With Multi-Spot Imaging and Electrophysiological Recordings: The Example of Cerebellar Network Dynamics

(paper)

Tognolina M., Monteverdi A., and D'Angelo E.

Frontiers in Cellular Neuroscience (2022). DOI: 10.3389/fncel.2022.805670

Acute Retina

A novel approach to the functional classification of retinal ganglion cells

A novel approach to the functional classification of retinal ganglion cells

(paper)

Hilgen G., Kartsaki E., Kartysh V., Cessac B. and Sernagor E.

Open Biol (2022). DOI: 0.1098/rsob.210367

Organoids

Human Retinal Organoids Provide a Suitable Tool for Toxicological Investigations: a Comprehensive Validation Using Drugs and Compounds Affecting the Retina

Human Retinal Organoids Provide a Suitable Tool for Toxicological Investigations: a Comprehensive Validation Using Drugs and Compounds Affecting the Retina

(paper)

Dorgau B., Georgiou M., Chaudhary A., Moya-Molina M., Collin J., Queen R., Hilgen G., Davey T., Hewitt P., Schmitt M., Kustermann S., Pognan F., Steel D. H., Sernagor E., Armstrong L., and Lako M.

Stem Cells Transl Med. (2022). DOI: 10.1093/stcltm/szab010

Acute Brain Slices

Implementation of biohybrid olfactory bulb on a high-density CMOS-chip to reveal large-scale spatiotemporal circuit information

Implementation of biohybrid olfactory bulb on a high-density CMOS-chip to reveal large-scale spatiotemporal circuit information

(paper)

Hu X., Khanzada S., Klütsch D.,Calegari F., and Amin H.

Biosensors and Bioelectronics (2022). DOI: 10.1016/j.bios.2021.113834

Acute Brain Slices

Non-Linear Frequency Dependence of Neurovascular Coupling in the Cerebellar Cortex Implies Vasodilation–Vasoconstriction Competition

Non-Linear Frequency Dependence of Neurovascular Coupling in the Cerebellar Cortex Implies Vasodilation–Vasoconstriction Competition

(paper)

Gagliano G., Monteverdi A., Casali S., Laforenza U., Gandini Wheeler-Kingshott C.A.M., D'Angelo E., and Mapelli L.

Cells (2022). DOI: 10.3390/cells11061047

Acute Brain Slices

3D two-photon brain imaging reveals dihydroartemisinin exerts antiepileptic effects by modulating iron homeostasis

3D two-photon brain imaging reveals dihydroartemisinin exerts antiepileptic effects by modulating iron homeostasis

(paper)

Shao C., Liu Y., Chen Z., Zhu H., Zhao J. and Qian Y.

Cell Chemical Biology (2021). DOI: 10.1016/j.chembiol.2021.12.006

Cardiomyocyte

All-Optical and Label-Free Stimulation of Action Potentials in Neurons and Cardiomyocytes by Plasmonic Porous Metamaterials

All-Optical and Label-Free Stimulation of Action Potentials in Neurons and Cardiomyocytes by Plasmonic Porous Metamaterials

(paper)

Bruno G. , Melle G. , Barbaglia A. , Iachetta G., Melikov R., Perrone M., Dipalo M., and Angelis F.D.

Advanced Science (2021). DOI: 10.1002/advs.202100627

Acute Brain Slices

Arhgap22 Disruption Leads to RAC1 Hyperactivity Affecting Hippocampal Glutamatergic Synapses and Cognition in Mice

Arhgap22 Disruption Leads to RAC1 Hyperactivity Affecting Hippocampal Glutamatergic Synapses and Cognition in Mice

(paper)

Longatti A., Ponzoni L., Moretto E., Giansante G., Lattuada N., Colombo M.N., Francolini M., Sala M., Murru L. , and Passafaro M.

Mol Neurobiol. (2021). DOI: 10.1007/s12035-021-02502-x

Organoids

Human derived cortical excitatory neurospheroids showed spontaneous activity on micro electrodes array

Human derived cortical excitatory neurospheroids showed spontaneous activity on micro electrodes array

(conf. proc.)

Muzzi L. , Falappa M., Maccione A. , Di Lisa D. , Frega M. , and Martinoia S.

IEEE (2021) DOI: 10.1109/NER49283.2021.9441261

Neuronal Cultures

A Monolayer System for the Efficient Generation of Motor Neuron Progenitors and Functional Motor Neurons from Human Pluripotent Stem Cells

A Monolayer System for the Efficient Generation of Motor Neuron Progenitors and Functional Motor Neurons from Human Pluripotent Stem Cells

(paper)

Cutarelli A., Martínez-Rojas V.A., Tata A., Battistella I., Rossi D., Arosio D., Musio C., and Conti L.

Cells (2021). DOI: 10.3390/cells10051127

Cardiomyocyte

Improving reliability and reducing costs of cardiotoxicity assessments using laser-induced cell poration on microelectrode arrays

Improving reliability and reducing costs of cardiotoxicity assessments using laser-induced cell poration on microelectrode arrays

(paper)

Iachetta G., Colistra N., Melle G., Deleye L., Tantussi F., Angelis F.D., and Dipalo M.

Toxicology and Applied Pharmacology (2021). DOI: 10.1016/j.taap.2021.115480

Acute Brain Slices

Sushi domain-containing protein 4 controls synaptic plasticity and motor learning

Sushi domain-containing protein 4 controls synaptic plasticity and motor learning

(paper)

Gonzalez-Calvo I., Iyer K., Carquin M., Khayachi A., Giuliani F. A., Sigoillot S. M., Vincent J., Seveno M., Veleanu M., Tahraoui S., Albert M., Vigy O., Bosso-Lefevre C., Nadjar Y., Dumoulin A., Triller A., Bessereau J-L., Rondi-Reig L., Isope P., and Selimi F.

eLife (2021) DOI: 10.7554/eLife.65712

Acute Retina

Transplanted pluripotent stem cell‐derived photoreceptor precursors elicit conventional and unusual light responses in mice with advanced retinal degeneration

Transplanted pluripotent stem cell‐derived photoreceptor precursors elicit conventional and unusual light responses in mice with advanced retinal degeneration

(paper)

Zerti D., Hilgen G., Dorgau B., Collin J., Ader M., Armstrong L., Sernagor E., and Lako M.

Stem Cells Journal (2021). DOI: 10.1002/stem.3365

Acute Brain Slices

Neuronal Glutamatergic Network Electrically Wired with Silent But Activatable Gap Junctions

Neuronal Glutamatergic Network Electrically Wired with Silent But Activatable Gap Junctions

(paper)

Ixmatlahua D. J., Vizcarra B., Gómez-Lira G., Romero-Maldonado I., Ortiz F., Rojas-Piloni G. and Gutiérrez R.

The Journal of Neuroscience (2020). DOI: https://doi.org/10.1523/JNEUROSCI.2590-19.2020

Organoids

Room temperature shipment does not affect the biological activity of pluripotent stem cell derived retinal organoids

Room temperature shipment does not affect the biological activity of pluripotent stem cell derived retinal organoids

(paper)

Georgiou M., Chichagova V., Hilgen G., Dorgau B., Sernagor E., Armstrong L. and Lako M.

Plos One (2020). DOI: https://doi.org/10.1371/journal.pone.0233860

Acute Brain Slices

A Claustrum in Reptiles and its role in Slow-Wave Sleep

A Claustrum in Reptiles and its role in Slow-Wave Sleep

(paper)

Norimoto H., Fenk L. A., Li H., Tosches M. A., Gallego-Flores T., Hain D., Reiter S., Kobayashi R., Macias A., Arends A., Klinkmann M. and Laurent G.

Nature (2020). DOI: https://doi.org/10.1038/s41586-020-1993-6

Acute Retina

Electrical Coupling of Heterotypic Ganglion Cells in the Mammalian Retina

Electrical Coupling of Heterotypic Ganglion Cells in the Mammalian Retina

(paper)

Puller C., Duda S., Lotfi E., Arzhangnia Y., Block C. T., Ahlers M. T. and Greschner M.

Journal of Neuroscience (2020). DOI: https://doi.org/10.1523/JNEUROSCI.1374-19.2019

Signal Processing

Neural field models for latent state inference: Application to large-scale neuronal recordings

Neural field models for latent state inference: Application to large-scale neuronal recordings

(paper)

Rule M. E., Schnoerr D., Hennig M. H. and Sanguinetti G.

PLOS Computational Biology (2019). DOI: https://doi.org/10.1371/journal.pcbi.1007442

Acute Retina

Investigating the Effects of Mechanical Stimulation on Retinal Ganglion Cell Spontaneous Spiking Activity

Investigating the Effects of Mechanical Stimulation on Retinal Ganglion Cell Spontaneous Spiking Activity

(paper)

Marrese M., Lonardoni D., Boi F., Hoorn H.V., Maccione A., Zordan S., Lannuzzi D. and Berdondini L.

Front. Cell. Neurosci. (2019). DOI: https://doi.org/10.3389/fnins.2019.01023

Neuronal Cultures

Transfer Entropy Based Connectivity Estimation of Spontaneously Firing Hippocampal Cultures on Multi Electrode Arrays

Transfer Entropy Based Connectivity Estimation of Spontaneously Firing Hippocampal Cultures on Multi Electrode Arrays

(conf. proc.)

Lama N., Hargreaves A.J., Stevens B., Mcginnity T.M.

International Joint Conference on Neural Networks (2019). DOI: 10.1109/IJCNN.2019.8851864

Organoids

Systematic Comparison of Retinal Organoid Differentiation from Human Pluripotent Stem Cells Reveals Stage Specific, Cell Line, and Methodological Differences

Systematic Comparison of Retinal Organoid Differentiation from Human Pluripotent Stem Cells Reveals Stage Specific, Cell Line, and Methodological Differences

(paper)

Mellough C. B., Collin J., Queen R., Hilgen G., Dorgau B., Zerti D., Felemban M., White K., Sernagor E., Lako M.

Stem Cell Translational Medicine (2019), DOI: 10.1002/sctm.18-0267

Acute Retina

Non-parametric Physiological Classification of Retinal Ganglion Cells in the Mouse Retina

Non-parametric Physiological Classification of Retinal Ganglion Cells in the Mouse Retina

(paper)

Jouty J., Hilgen G., Sernagor E. and Hennig M.H.

Front. Cell. Neurosci. (2018). DOI: https://doi.org/10.3389/fncel.2018.00481

Acute Brain Slices

High Density Multi Electrode Array: a new tool to monitor seizure-like activity evoked by different convulsant drugs

High Density Multi Electrode Array: a new tool to monitor seizure-like activity evoked by different convulsant drugs

(conf. proc.)

Sessolo M., Ugolini A., Maccione A., Gandolfo M., Corsi M., Virginio C.

SFN (2018). San Diego, CA, USA.

Organoids

Development of central nervous system 3D in vitro models to study molecular mechanisms and develop therapeutic strategies for motor neuron diseases

Development of central nervous system 3D in vitro models to study molecular mechanisms and develop therapeutic strategies for motor neuron diseases

(conf. proc.)

Faravelli I., Mapelli L., Tamanini S., Cordiglieri C., Rizzuti M., Forotti G., Bresolin N., Comi G.P., Nizzardo M., Corti S.

SFN (2018). San Diego, CA, USA.

Acute Brain Slices

Early Appearance and Spread of Fast Ripples in the Hippocampus in a Model of Cortical Traumatic Brain Injury

Early Appearance and Spread of Fast Ripples in the Hippocampus in a Model of Cortical Traumatic Brain Injury

(paper)

Ortiz F., Karel Zapfe W.P., Draguhn A. and Gutiérrez R.

Journal of Neuroscience (2018). DOI: https://doi.org/10.1523/JNEUROSCI.3507-17.2018

Signal Processing

Identification of excitatory-inhibitory links and network topology in large-scale neuronal assemblies from multi-electrode recordings

Identification of excitatory-inhibitory links and network topology in large-scale neuronal assemblies from multi-electrode recordings

(paper)

Pastore V. P., Massobrio P., Godjoski A. and Martinoia S.

PLOS Computational Biology (2018). DOI: https://doi.org/10.1371/journal.pcbi.1006381

Cardiomyocyte

Plasmonic meta-electrodes allow intracellular recordings at network level on high-density CMOS-multi-electrode arrays

Plasmonic meta-electrodes allow intracellular recordings at network level on high-density CMOS-multi-electrode arrays

(paper)

Dipalo M., Melle G., Lovato L., Jacassi A., Santoro F., Caprettini V., Schirato A., Alabastri A., Garoli D., Bruno G., Tantussi F., De Angelis F.

Nature Nanotechnology (2018). DOI: https://doi.org/10.1038/s41565-018-0222-z

Technology

Exploiting All Programmable SoCs in Neural Signal Analysis: A Closed-Loop Control for Large-Scale CMOS Multielectrode Arrays

Exploiting All Programmable SoCs in Neural Signal Analysis: A Closed-Loop Control for Large-Scale CMOS Multielectrode Arrays

(paper)

Seu G. P., Angotzi G. N., Boi F., Raffo L., Berdondini L., and Meloni P.

IEEE Transactions on Biomedical Circuits and Systems (2018). DOI: 10.1109/TBCAS.2018.2830659

Organoids

Human‐Induced Pluripotent Stem Cells Generate Light Responsive Retinal Organoids with Variable and Nutrient‐Dependent Efficiency

Human‐Induced Pluripotent Stem Cells Generate Light Responsive Retinal Organoids with Variable and Nutrient‐Dependent Efficiency

(paper)

Hallam D., Hilgen G., Dorgau B., Zhu L., Yu M., Bojic S., Hewitt P., Schmitt M., Uteng M., Kustermann S., Steel D., Nicholds M., Thomas R., Treumann A., Porter A., Sernagor E., Armstrong L. and Lako M.

Stem Cells (2018). DOI: https://doi.org/10.1002/stem.2883

Signal Processing

Spike Train Synchrony Analysis of Neuronal Cultures

Spike Train Synchrony Analysis of Neuronal Cultures

(conf. proc.)

Lama N., Hargreaves A., Stevens B. and McGinnity T.M.

International Joint Conference on Neural Networks (IJCNN) (2018). DOI: 10.1109/IJCNN.2018.8489728

Acute Brain Slices

Purkinje cells firing recorded by a high density multi-electrode array: a new tool for compounds validation

Purkinje cells firing recorded by a high density multi-electrode array: a new tool for compounds validation

(conf. proc.)

Ugolini A., Sessolo M., Maccione A., Bettini E., Gandolfo M., Corsi M., Virginio C.

FENS conference (2018). Berlin, Germany.

Neuronal Cultures

State-dependent representation of stimulus-evoked activity in high-density recordings of neural cultures

State-dependent representation of stimulus-evoked activity in high-density recordings of neural cultures

(paper)

Nieus T., D’Andrea V., Amin H., Di Marco S., Safaai H., Maccione A., Berdondini L. and Panzeri S.

Scientific Reports (2018). DOI: 10.1038/s41598-018-23853-x

Acute Retina

Eliminating Glutamatergic Input onto Horizontal Cells Changes the Dynamic Range and Receptive Field Organization of Mouse Retinal Ganglion Cells

Eliminating Glutamatergic Input onto Horizontal Cells Changes the Dynamic Range and Receptive Field Organization of Mouse Retinal Ganglion Cells

(paper)

Stroh S., Puller C., Swirski S., Holzel M., van der Linde L.I.S., Segelken J., Schultz K, Block C., Monyer H., Willecke K., Weiler R., Greschner M., Janssen-Bienhold U. and Dedek K.

The Journal of Neuroscience (2018). DOI: https://doi.org/10.1523/JNEUROSCI.0141-17.2018

Technology

Fabrication of Multielectrode Arrays for Neurobiology Applications

Fabrication of Multielectrode Arrays for Neurobiology Applications

(book chapter)

Malerba M., Amin H., Angotzi G. N., Maccione A., Berdondini L.

Cell-Based Microarrays, Methods in Molecular Biology, Editors: Ertl P., Rothbauer M., Springer (2018). DOI: https://doi.org/10.1007/978-1-4939-7792-5_12

Neuronal Cultures

Developmental excitatory-to-inhibitory GABA-polarity switch is disrupted in 22q11.2 deletion syndrome: a potential target for clinical therapeutics

Developmental excitatory-to-inhibitory GABA-polarity switch is disrupted in 22q11.2 deletion syndrome: a potential target for clinical therapeutics

(paper)

Amin H., Marinaro F., De Pietri Tonelli D., Berdondini L.

Scientific Report (2017). DOI: 10.1038/s41598-017-15793-9

Signal Processing

SPICODYN: A Toolbox for the Analysis of Neuronal Network Dynamics and Connectivity from Multi-Site Spike Signal Recordings

SPICODYN: A Toolbox for the Analysis of Neuronal Network Dynamics and Connectivity from Multi-Site Spike Signal Recordings

(paper)

Pastore V. P., Godjoski A., Martinoia S., Massobrio P.

Neuroinform (2017). DOI: https://doi.org/10.1007/s12021-017-9343-z

Technology

Recurrently connected and localized neuronal communities initiate coordinated spontaneous activity in neuronal networks

Recurrently connected and localized neuronal communities initiate coordinated spontaneous activity in neuronal networks

(paper)

Lonardoni D., Hayder A., Di Marco S., Maccione A., Berdondini L., Nieus T.

PLOS, computation biology (2017). DOI: https://doi.org/10.1371/journal.pcbi.1005672

Neuronal Cultures

Selective Targeting of Neurons with Inorganic Nanoparticles: Revealing the Crucial Role of Nanoparticle Surface Charge

Selective Targeting of Neurons with Inorganic Nanoparticles: Revealing the Crucial Role of Nanoparticle Surface Charge

(paper)

Dante S., Petrelli A., Petrini E., Marotta E., Maccione A., Alabastri A., Quarta A., De Donato F., Ravasenga T., Sathya A., Cingolani R., Proietti Zaccaria R., Berdondini L., Barberis A., Pellegrino T.

ACS Nano (2017). DOI:10.1021/acsnano.7b00397

Acute Brain Slices

Polyethylene glycol restores axonal conduction after corpus callosum transection

Polyethylene glycol restores axonal conduction after corpus callosum transection

(paper)

Bamba R., Riley D. C., Boyer R. B., Pollins A.C., Shack R.B., Thayer W.P.

Neural regeneration research (2017). DOI: 10.4103/1673-5374.206645

Neuronal Cultures

High-resolution bioelectrical imaging of Aβ-induced network dysfunction on CMOS-MEAs for neurotoxicity and rescue studies

High-resolution bioelectrical imaging of Aβ-induced network dysfunction on CMOS-MEAs for neurotoxicity and rescue studies

(paper)

Amin H., Nieus T., Lonardoni D., Maccione A. and Berdondini L.

Scientific Reports (2017). DOI: 10.1038/s41598-017-02635-x

Signal Processing

Unsupervised Spike Sorting for Large-Scale, High-Density Multielectrode Arrays

Unsupervised Spike Sorting for Large-Scale, High-Density Multielectrode Arrays

(paper)

Hilgen G., Sorbaro M, Pirmoradian S, Muthmann J-O., Kepiro I, Ullo S., Rmairez C. J., Encinas A. P., Maccione A., Berdondini L., Murino V., Sona D., Cella Zanacchi F., Sernagor E., Hennig M.

Cell Reports (2017). DOI: http://dx.doi.org/10.1016/j.celrep.2017.02.038

Acute Retina

Pan-retinal characterisation of Light Responses from Ganglion Cells in the Developing Mouse Retina

Pan-retinal characterisation of Light Responses from Ganglion Cells in the Developing Mouse Retina

(paper)

Hilgen G., Pirmoradian S., Pamplona D., Kornprobst P., Cessac B., Hennig M., Sernagor E.

Sci Rep. (2017). DOI: 10.1038/srep42330

Acute Brain Slices

Exploiting high content datasets recorded with high density Multi Electrode Array to investigate compounds functional effects with LTP protocols in cortico-hippocampal brain slices

Exploiting high content datasets recorded with high density Multi Electrode Array to investigate compounds functional effects with LTP protocols in cortico-hippocampal brain slices

(conf. proc.)

Zordan S., Ugolini A., Virginio C., Corsi M., Lonardoni D., Gandolfo M., Maccione A. and Berdondini L.

SFN conference (2016). San Diego, CA, USA.

Acute Retina

Dampening Spontaneous Activity Improves the Light Sensitivity and Spatial Acuity of Optogenetic Retinal Prosthetic Responses

Dampening Spontaneous Activity Improves the Light Sensitivity and Spatial Acuity of Optogenetic Retinal Prosthetic Responses

(paper)

Barrett J. M., Hilgen G. and Sernagor E.

Sci Rep. (2016). DOI: 10.1038/srep33565

Technology

Specific Neuron Placement on Gold and Silicon Nitride-Patterned Substrates through a Two-Step Functionalization Method

Specific Neuron Placement on Gold and Silicon Nitride-Patterned Substrates through a Two-Step Functionalization Method

(paper)

Mescola A., Canale C., Prato M., Diaspro A., Berdondini L., Maccione A., and Dante S.

Langmuir (2016). DOI: 10.1021/acs.langmuir.6b01352.

Acute Retina

Rank order coding: a retinal information decoding strategy revealed by large-scale multielectrode array retinal recordings.

Rank order coding: a retinal information decoding strategy revealed by large-scale multielectrode array retinal recordings.

(paper)

Portelli G., Barrett J.M., Hilgen G., Masquelier T., Maccione A., Di Marco S., Berdondini L., Kornprobst P., Sernagor E.

ENeuro (2016). DOI: 10.1523/ENEURO.0134-15.2016.

Neuronal Cultures

Electrical responses and spontaneous activity of human iPS-derived neuronal networks characterized for three-month culture with 4096-electrode arrays

Electrical responses and spontaneous activity of human iPS-derived neuronal networks characterized for three-month culture with 4096-electrode arrays

(paper)

Amin H., Maccione A., Marinaro F., Zordan S., Nieus T., Berdondini L.

Front. Neurosci. (2016). DOI: 10.3389/fnins.2016.00121.

Signal Processing

ToolConnect: a functional connectivity toolbox for in vitro networks

ToolConnect: a functional connectivity toolbox for in vitro networks

(paper)

Pastore V. P., Poli D., Godjoski A., Martinoia S., Massobrio P.

Frontiers in Neuroinformatics (2016). DOI: 10.3389/fninf.2016.00013

Neuronal Cultures

State-Dependent Propagation of Neuronal Sub-Population in Spontaneous Synchronized Bursts

State-Dependent Propagation of Neuronal Sub-Population in Spontaneous Synchronized Bursts

(paper)

Yuichiro Y., Ryohei K. and Hirokazu T.

Front. Syst. Neurosci. (2016). DOI: 10.3389/fnsys.2016.00028.

Neuronal Cultures

Propagation and synchronization of reverberatory bursts in developing cultured networks

Propagation and synchronization of reverberatory bursts in developing cultured networks

(paper)

Huang CH., Huang YT., Chen CC., Chan CK.

J Comput Neurosci (2016). DOI: 10.1007/s10827-016-0634-4.

Signal Processing

Spike detection for large neural populations using high density multielectrode arrays

Spike detection for large neural populations using high density multielectrode arrays

(paper)

Muthmann O., Amin H., Sernagor E., Maccione A., Panas D., Berdondini L., Bhalla U. S., Hennig M.

Frontiers in Neuroinformatics (2015). ISSN:1662-5196 DOI:10.3389/fninf.2015.00028

Neuronal Cultures

High-density MEA recordings unveil the dynamics of bursting events in Cell Cultures

High-density MEA recordings unveil the dynamics of bursting events in Cell Cultures

(conf. proc.)

Lonardoni D., Di Marco S., Amin H., Maccione A., Berdondini L., Nieus T.

Engineering in Medicine and Biology Society - 37th Annual International Conference of the IEEE (2015). DOI: 10.1109/EMBC.2015.7319212.

Neuronal Cultures

Investigating cell culture dynamics combining high density recordings with dimensional reduction techniques

Investigating cell culture dynamics combining high density recordings with dimensional reduction techniques

(conf. proc.)

Nieus T. , Di Marco S. , Maccione A. , Amin H. , Berdondini L.

Engineering in Medicine and Biology Society - 37th Annual International Conference of the IEEE (2015). DOI: 10.1109/EMBC.2015.7319211.

Neuronal Cultures

Functional connectivity in in vitro neuronal assemblies

Functional connectivity in in vitro neuronal assemblies

(paper)

Polo D., Pastore V.P., and Massobrio P.

Frontiers (2015). DOI: 10.3389/fncir.2015.00057

Technology

Microelectronics, bioinformatics and neurocomputation for massive neuronal recordings in brain circuits with large scale multielectrode array probes

Microelectronics, bioinformatics and neurocomputation for massive neuronal recordings in brain circuits with large scale multielectrode array probes

(paper)

Maccione A., Gandolfo M., Zordan S., Amin H., Di Marco S., Nieus T., Angotzi G.N., Berdondini L.

Brain Research Bulletin (2015). DOI: https://doi.org/10.1016/j.brainresbull.2015.07.008

Neuronal Cultures

Sloppiness in Spontaneously Active Neuronal Networks

Sloppiness in Spontaneously Active Neuronal Networks

(paper)

Panas D., Amin H., Maccione A., Muthmann O., van Rossum M., Berdondini L. and Hennig M.

Journal of Neuroscience (2015). DOI: 10.1523/JNEUROSCI.4421-14.2015.

Neuronal Cultures

Functional Connectivity Estimation over Large Networks at Cellular Resolution based on Electrophysiological Recordings and Structural Prior

Functional Connectivity Estimation over Large Networks at Cellular Resolution based on Electrophysiological Recordings and Structural Prior

(paper)

Ullo S. , Nieus T. , Sona D. , Maccione A. , Berdondini L. and Murino V.

Frontiers in Neuroanatomy (2014), DOI: 10.3389/fnana.2014.00137.

Signal Processing

Characterizing neural population response with high-density multielectrode arrays

Characterizing neural population response with high-density multielectrode arrays

(conf. proc.)

Pirmoradian S., Hilgen G., Muthmann O., Maccione A., Bhalla U., Berdondini L., Sernagor E., Hennig M. H.

SFN conference (2014). Washington, DC, USA.

Technology

Large-Scale recording of light-evoked responses in the retinal ganglion cell layer of the explanted retina: A new HD experimental platform

Large-Scale recording of light-evoked responses in the retinal ganglion cell layer of the explanted retina: A new HD experimental platform

(conf. proc.)

Di Marco S., Maccione A., Hilgen G., Pirmoradian S., Nieus T., Hennig M., Sernagor E., Berdondini L.

SFN November (2014). Washington, DC, USA.

Technology

Structured neuronal networks investigated by high-resolution MEAs

Structured neuronal networks investigated by high-resolution MEAs

(conf. proc.)

Simi A., Bosca A., Maccione A., Nieus T., Brandi F., Dante S. and Berdondini L.

FENS Forum (2012) Barcelona, Spain.

Acute Retina

A high-resolution experimental platform for large-scale recording of light-evoked responses in the retinal ganglion cell layer

A high-resolution experimental platform for large-scale recording of light-evoked responses in the retinal ganglion cell layer

(conf. proc.)

Di Marco S., Maccione A., Nieus T., Hennig M., Pirmoradian S., Hilgen G., Sernagor E., Berdondini L.

FENS Conference (2014). Milan, Italy.

Neuronal Cultures

Alzheimer's disease (AD) in-vitro model: a novel drug screening approach on 4096-microelectrode recording arrays

Alzheimer's disease (AD) in-vitro model: a novel drug screening approach on 4096-microelectrode recording arrays

(conf. proc.)

Amin H., Maccione A., Nieus T., Berdondini L.

9th FENS Meeting (2014). Milan, Italy.

Acute Retina

High Resolution Large-Scale Recordings of Light Responses from Mouse Retinal Ganglion Cells

High Resolution Large-Scale Recordings of Light Responses from Mouse Retinal Ganglion Cells

(conf. proc.)

Hilgen G., Maccione A., Di Marco S., Berdondini L., Sernagor E.

MEA meeting (2014). Reutlingen, Germany.

Neuronal Cultures

Differentiation and functional integration of adult-born hippocampal neurons: a study on high-resolution microelectrode arrays (MEA)

Differentiation and functional integration of adult-born hippocampal neurons: a study on high-resolution microelectrode arrays (MEA)

(conf. proc.)

Simi A., Maccione A., Nieus T., De Pietri Tonelli D., Berdondini L.

9th FENS Meeting (2014). Milan, Italy.

Acute Brain Slices

Asynchronous GABA Release Is a Key Determinant of Tonic Inhibition and Controls Neuronal Excitability: A Study in the Synapsin II-/- Mouse

Asynchronous GABA Release Is a Key Determinant of Tonic Inhibition and Controls Neuronal Excitability: A Study in the Synapsin II-/- Mouse

(paper)

Medrihan L., Ferrea E., Greco B., Baldelli P. and Benfenati F.

Cerebral Cortex (2014). DOI: 10.1093/cercor/bhu141

Technology

3D plasmonic hollow nanoantennas as tools for neuroscience applications

3D plasmonic hollow nanoantennas as tools for neuroscience applications

(conf. proc.)

Dipalo M., Malerba M., Messina G. C., La Rocca R., Amin H., Maccione A., Berdondini L., De Angelis F.

CLEO: Science and Innovations (2014). San Jose, CA, USA. DOI: https://doi.org/10.1364/CLEO_SI.2014.STh4H.3

Signal Processing

A computational model of hippocampal neuronal networks: the role of connectivity in the appearance of synchronized bursting events

A computational model of hippocampal neuronal networks: the role of connectivity in the appearance of synchronized bursting events

(conf. proc.)

Lonardoni D., Berdondini L., Nieus T.

EMRS spring meeting (2014). Lille, France.

Neuronal Cultures

High resolution microelectrode arrays (MEAs) for reliably studying an in-vitro neuronal network model of induced-Alzheimer's disease

High resolution microelectrode arrays (MEAs) for reliably studying an in-vitro neuronal network model of induced-Alzheimer's disease

(conf. proc.)

Amin H., Maccione A., Nieus T., Berdondini L.

Biosensors (2014). Melbourne, Australia.

Technology

3D plasmonic nanoelectrodes for intracellular recording of large-scale neuronal networks

3D plasmonic nanoelectrodes for intracellular recording of large-scale neuronal networks

(conf. proc.)

Dipalo M., Malerba M., Simi A., Amin H., Maccione A., Berdondini L., De Angelis F.

EMRS spring meeting (2014). Lille, France.

Acute Retina

Following the Ontogeny of Retinal Waves: Pan-Retinal Recordings of Population Dynamics in the Neonatal Mouse

Following the Ontogeny of Retinal Waves: Pan-Retinal Recordings of Population Dynamics in the Neonatal Mouse

(paper)

Maccione A., Hennig M., Gandolfo M., Muthmann O., van Coppenhagen J., Eglen S. J., Berdondini L. and Sernagor E.

The Journal of Physiology (2014). DOI: 10.1113/jphysiol.2013.262840.

Acute Retina

Mapping large scale retinal population activity with high density multielectrode arrays

Mapping large scale retinal population activity with high density multielectrode arrays

(conf. proc.)

Pirmoradian S., Hilgen G., Muthman O., Maccione A., Bhalla U., Berdondini L., Sernagor E., Hennig M.H.

Cosyne Meeting (2014). Salt Lake City, UT, USA.

Technology

Integration of microstructured scaffolds, neurons, and multielectrode arrays

Integration of microstructured scaffolds, neurons, and multielectrode arrays

(book chapter)

Simi A., Amin H., Maccione A., Nieus T., Berdondini L.

“Brain Extracellular Matrix in Health and Disease” Ed. Dityatev, Wehrle-Haller and Pitkänen, Elsevier 1st Edition (2014). DOI: 10.1016/B978-0-444-63486-3.00017-7

Technology

Micro-/Nano-Technologies and Microelectronics for Neuroscience Research and Applications

Micro-/Nano-Technologies and Microelectronics for Neuroscience Research and Applications

(conf. proc.)

Simi A., Amin H., Maccione A., Nieus T., Di Marco S., Dipalo M., Talaei S., Koudelka-Hep M., van der Wal P. D., de Rooij N. F., Berdondini L.

6th European Conference of the International Federation for Medical and Biological Engineering IFMBE Proceedings (2015). DOI: https://doi.org/10.1007/978-3-319-11128-5_194

Technology

Brain Function: Novel Technologies Driving Novel Understanding

Brain Function: Novel Technologies Driving Novel Understanding

(book chapter)

Assad J. A. , Berdondini L. , Cancedda L. , De Angelis F. , Diaspro A. , Dipalo M. , Fellin T. , Maccione A., Panzeri S. and Sileo L.

Bioinspired Approaches for Human-Centric Technologies, Cingolani, Roberto (Ed.) (2014). DOI: 10.1007/978-3-319-04924-3

Technology

Novel 3D plasmonic nano-electrodes for cellular investigations and neural interfaces

Novel 3D plasmonic nano-electrodes for cellular investigations and neural interfaces

(conf. proc.)

Malerba M., Dipalo M., Messina G. C., Amin H., La Rocca R., Shalabaeva V., Simi A., Maccione A., Berdondini L.

SPIE 9166, Biosensing and Nanomedicine VII (2014). DOI: 10.1117/12.2066274

Technology

Active Pixel Sensor Multielectrode Array for High Spatiotemporal Resolution

Active Pixel Sensor Multielectrode Array for High Spatiotemporal Resolution

(book chapter)

Berdondini L., Bosca A. , Nieus T., Maccione A.

Nanotechnology and Neuroscience: Nano-electronic, Photonic and Mechanical Neuronal Interfacing (2014). DOI: https://doi.org/10.1007/978-1-4899-8038-0_7

Signal Processing

Tools for analysis of high-density multielectrode recordings in the neonatal mouse retina

Tools for analysis of high-density multielectrode recordings in the neonatal mouse retina

(conf. proc.)

Hennig M., Muthmann O., Maccione A., Gandolfo M., Eglen S., Berdondini L. and Sernagor E.

Front. Neuroinform (2013). DOI: 10.3389/conf.fninf.2013.08.00004

Acute Retina

Deciphering Retinal Functional Circuitry: High Resolution Large-Scale Population Recordings From The Mouse Retinal Ganglion Cell Layer

Deciphering Retinal Functional Circuitry: High Resolution Large-Scale Population Recordings From The Mouse Retinal Ganglion Cell Layer

(conf. proc.)

Sernagor E., Hilgen G., Barrett J., Hennig M., Maccione A., Berdondini L.

European Retina Meeting ERM (2013). Alicante, Spain.

Acute Brain Slices

Can a pro-seizures effect be predicted? Evaluation of two technological approaches in hippocampal slices

Can a pro-seizures effect be predicted? Evaluation of two technological approaches in hippocampal slices

(conf. proc.)

Ugolini A., Maccione A., Gandolfo M., Corsi M., Virginio C.

Safety Pharmacology Society Meeting (2013). Rotterdam, The Netherlands.

Acute Brain Slices

Dentate gyrus network dysfunctions precede the symptomatic phase in a genetic mouse model of seizures

Dentate gyrus network dysfunctions precede the symptomatic phase in a genetic mouse model of seizures

(paper)

Toader O., Forte N., Orlando M., Ferrea E., Raimondi A., Baldelli P., Benfenati F. and Medrihan L.

Front Cell Neurosci. (2013). DOI: 10.3389/fncel.2013.00138.

Signal Processing

Homeostasis in large networks of neurons through the Ising model - do higher order interactions matter?

Homeostasis in large networks of neurons through the Ising model - do higher order interactions matter?

(conf. proc.)

Panas D., Maccione A., Berdondini L. & Hennig M.

CNS Meeting - BMC Neuroscience (2013). Paris, France. DOI: https://doi.org/10.1186/1471-2202-14-S1-P166

Signal Processing

Estimating the fraction of falsely detected spikes in high density microelectrode array recordings based on correlations

Estimating the fraction of falsely detected spikes in high density microelectrode array recordings based on correlations

(conf. proc.)

Muthmann J-O., Amin H., Maccione A., Sernagor E., Berdondini L., Hennig M. and Bhalla U.S.

CNS Meeting - BMC Neuroscience (2013). Paris, France. DOI: https://doi.org/10.1186/1471-2202-14-S1-P25

Neuronal Cultures

Investigating the interplay between intrinsic and evoked activities in cultured neuronal networks by dimensional reduction techniques and high-density MEAs

Investigating the interplay between intrinsic and evoked activities in cultured neuronal networks by dimensional reduction techniques and high-density MEAs

(conf. proc.)

Nieus T., Maccione A. and Berdondini L.

CNS Meeting 2013 - BMC Neuroscience (2013). DOI: 10.1186/1471-2202-14-S1-P24.