Explore new dimensions in brain research
Brain/CorticalOrganoids
Retinal Organoids
Spheroids
Scaffold/matrix-based 3D cultures
In vitro Brain Organoids or Spheroids reproduce key brain in-vivo organization features as cell–cell 3-dimensional interactions or tissue-specific architecture. This makes models a great resource for assessing the efficacy of drugs in brain disease studies and for toxicological and compound screening. 3Brain’s single-well HD-MEAs and CorePlate™ multiwell can measure functional activity from brain organoids at an unprecedented high spatial resolution.
Advantages of 3Brain technology with brain organoids are:
Label-free functional monitoring of whole organoids with single-cell spiking activity resolution.
Improved statistical significance measuring from thousands of neurons simultaneously
Multiple sample recordings: 3Brain’s HD-MEAs have a sensing area of up to 25mm², allowing to record multiple spheroids in a single experiment.
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Location to specific products and samples within 3Brain's resources
(paper)
Bioengineering (2023) DOI: 10.3390/bioengineering10040449
(paper)
Journal of Cellular and Molecular Medicine (2023). DOI: 10.1111/jcmm.17670
(paper)
Stem Cells Transl Med. (2022). DOI: 10.1093/stcltm/szab010