Explore new dimensions in brainresearch
Brain/CorticalOrganoids
Retinal Organoids
Spheroids
Scaffold/matrix-based 3D cultures
In vitro Brain Organoids or Spheroids reproduce key brain in-vivo organization features as cell-cell 3-dimensional interactions or tissue-specific architecture. Therefore, such models are a great resource for assessing the efficacy of drugs in brain disease studies and for toxicological and compound screening. 3Brain’s single-well HD-MEAs and CorePlate™ multiwell can measure the functional activity from brain organoids at a high spatial resolution never provided before.
Advantages of 3Brain technology with brain organoids are:
Label-free functional monitoring of whole organoids with single cell spiking activity resolution
Improved statistical significance measuring from thousands of neurons simultaneously
Multiple sample recordings: 3Brain’s HD-MEAs have a sensing area of up to 25mm², allowing to record multiple spheroids in a single experiment.
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Location to specific products and samples within 3Brain's resources
(selected papers)
Plos One (2020). DOI: https://doi.org/10.1371/journal.pone.0233860
(selected papers)
Stem Cell Translational Medicine (2019), DOI: 10.1002/sctm.18-0267
(conf. proc.)
SFN (2018). San Diego, CA, USA.