Tech Specs

Perform in vitro electrophysiology with our most accessible high-end technology based HD-MEA system

Shed new light on neuronal network complexity with 4096 electrodes sampled at 18 kHz

BioCAM X

Overview

Small footprint, large yields

For this unique Microelectrode array (MEA) platform, we combined state-of-the-art technology, high quality materials and functional design to create an outstandingly compact and easy to use device.

Featuring 4096 recording electrodes sampled simultaneously at 18 kHz, it provides several orders of magnitude more data points than can be obtained with conventional passive Multielectrode Arrays (MEAs).

All these features allow the recording of electrophysiological signals ranging from slow large-population field potentials to fast single-cell spiking activity over a large bandwidth.

BioCAM X platform delivers unique insights into several in vitro electrophysiological models, such as neuronal cell cultures, brain slices, retina preparations and cardiac cell cultures.

A compact microelectrode system

BioCAM X's small footprint allows easy integration with lab equipment commonly used in in vitro electrophysiology, such as microscopes, perfusion and patch-clamp systems.

"Plug-and-record" quick system

BioCAM X has a two-position button for locking in our HD-MEA chips. Simply one click to lock the chip in and immediately start to visualize and record your data on BrainWave's visual interface. Unlocking it is just as easy.

A compact MEA platform

BioCAM X's small footprint allows easy integration with lab equipment commonly used in electrophysiology, such as microscopes, and perfusion and patch-clamp systems.

"Plug-and-record" quick system

BioCAM X has the easiest mechanical system for plugging in MEA chips. Just one click to lock the chip and to start immediately to visualize and record your data on the BrainWave's visual interface. Unlocking it is just as easy.

Unique feature

Anti-Spill barrier

When a single-well HD-MEA is inserted and locked into its bay, a barrier comes down separating the downstream electronics. This prevents circuitry damage in case of accidental overflow of liquids

Unique feature

Anti-Spill barrier

When the HD-MEA probe is inserted and locked into its bay, a barrier comes down separating the downstream electronics. This prevents circuitry damage in case of accidental overflow of liquids

Unique feature

Anti-Spill barrier

When the HD-MEA probe is inserted and locked into its bay, a barrier comes down separating the downstream electronics. This prevents circuitry damage in case of accidental overflow of liquids

When the HD-MEA probe is inserted and locked into its bay, a barrier comes down separating the downstream electronics. This prevents circuitry damage in case of accidental overflow of liquids

BioCAM X - the initial all-in-one high density microelectrode array platform

All-in-One

BioCAM X incorporates further optional functionalities, which come as separate modules in most MEA-systems, such as a temperature control system and a programmable current driven electrical stimulator.

All-in-One

BioCAM X incorporates further optional functionalities, which come as separate modules in most MEA-systems, such as a temperature control system and an electrical programmable current-driven stimulator.

BioCAM X - the initial all-in-one high density microelectrode array platform

Under the case

Hover on the BioCAM X to discover more!

Integrated Stimulator

4 independently programmable current stimulator channels

Locking System

single two-position button for locking/unlocking

Advanced External Case

crafted from aluminium to make it robust to electromagnetic and mechanical noise

Magnetic Plate

to attach magnetic perfusion holders

Anti-spill barrier

to prevent circuitry damage due to liquid overflow

Temperature Control

integrated heating and cooling system

ACCESSORIES

Accessories

Expand your experimental capabilities

We provide a series of accessories which enables users to get the best from their BioCAM X platform, such as an IO Connector Box to expand connectivity.

Find out more

ACCESSORIES

Expand your experimental capabilities

We provide a series of accessories which enable users to get the best from the BioCAM X platform, such as an integrated stimulus generator. Find out more        

CONSUMABLES

CONSUMABLES

Single-Well HD-MEAs

CMOS-based high density multielectrode arrays (HD-MEAs) are multi-use devices with 4096 recording electrodes for high resolution in vitro extracellular electrophysiology.

Different models are available for meeting different needs.

See more

MEA probes

CMOS HD-MEA

CMOS-based high density multielectrode arrays (HD-MEAs) are multi-use devices with 4096 recording electrodes for high resolution in-vitro extracellular electrophysiology. The chip is based on CMOS technology and is packaged onto a substrate together with a glass reservoir.

Different models for different needs are available. See more       

HD-MEA electrodes are coated with Pt to provide a stable and fully biocompatible surface. The quality of the recording is ensured by the impressive signal-to-noise ratio, as you can appreciate from our video samples section. See videos        

Software

BrainWave

BioCAM X is supplied with the BrainWave software, which provides powerful online and offline visualization and analysis tools for electrophysiological signals, while storing all your data in an open-source HDF5 format.

Software

BrainWave

BioCAM X is supplied with the latest BrainWave software version, which provides powerful visualization and analysis tools for electrophysiological signals during and after your experiments and stores all your data in HDF5 format.

3Brain's BrainWave 4 software in use

Resources

Here you can find useful resources for your BioCAM X

Tech specs

Main Controller

Computational core

Intel®'s Cyclone® IV FPGA 1Gbps

Data resolution

12 bit

Number of simultaneous recording channels

4096

Sampling frequency (full-array)

18 kHz / electrode

Region-of-interest

1 - 4 independent subsets of electrodes (up to 64 kHz sampling frequency)

Temperature control

Active heating and cooling system

Data interface

Mini Camera Link™ (SDR)

Ground reference

External

HD-MEA compatibility

Prime, Arena, Stimulo

Control software compatibility

BrainWave X (v.3) or higher

Inputs

Two analog inputs (-3.3 V to 3.3 V) or triggers (LV-TTL)

Stimulation Module

Integrated stimulation module

Yes (optional)

Internal (on-chip) stimulation sites

16 (only for HD-MEA Stimulo)

External stimulation sites

4 differential channels (accesible with optional connector box)

Current stimulus generator

Yes

Number of channels

4

Maximum amplitude

+/- 1 mA

Amplitude resolution

10 µA

Time resolution

10 µs

Physical specs

Body material

Anodized aluminum and stainless steel

Locking mechanism

Two-position (lock/unlock) push button

Protection from liquid spill over

Anti-spill barrier v. 1

Dimensions (W x D x H)

160 x 205 x 38 mm / 6.30 x 8.07 x 1.50 inches

Weight

1.36 kg / 3 pounds

Have any questions? Book a chat or email us, as our neuroscientist team is here to assist you.
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