In-Plate Intelligence

Bringing you CorePlate™: the next-generation microelectrode array system for drug discovery and neuronal networks research

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The 3Brain - Massimo Grattarola Award has begun for 2022!

The Award aims to support young researchers into the start of their career. The winner will be awarded €15,000.

Head in to review the conditions and begin your application!

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Submit your email now to recieve a reminder ahead of time for the next award:

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HyperCAM Alpha

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HyperCAM Alpha

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CorePlate™ Multiwells

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CorePlate™ Multiwells

CorePlate™ Multiwells

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HyperCAM Alpha

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HyperCAM Alpha

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CorePlate™ Multiwells

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CorePlate™ Multiwells

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Multiwell
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Single-Well
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Software
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Accessories
3Brain's HyperCAM Alpha

HyperCAM Alpha

The 6-well, CorePlate™-powered multi-well platform delivering high-resolution functional screening.

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3Brain's CorePlate™ Multiwells

CorePlate™ Multiwells

CorePlate™ processing capabilities convert multi-well plates into smart objects.

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The only fully bi-directional HD-MEA (microelectrode array) platform for 2D and 3D in vitro electrophysiology.

BioCAM DupleX

The only fully bi-directional HD-MEA platformfor 2D and 3D in vitro electrophysiology.

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Our genuine HD-MEA (microelectrode array) platform with everything you need for in vitro neuronal physiology. - BioCAM X

BioCAM X

Our genuine HD-MEA platform with everything you need for in vitro neuronal network physiology.

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3Brain's Single-Well HD-MEAs

Single-Well HD-MEAs

A varied selection of high-density MEAs to match your precise research needs with the single-well devices.

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BrainWave 5

The software that combines all you need to acquire, analyze and manage data from CorePlate™ multi-wells.

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BrainWave 4

The companion for our single-well HD-MEAs to visualize, record and analyze neural cell activity in real time.

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IO Connector Box - 3Brain Accessories: featuring multiple modules for the CMOS-MEA channels

Single-Well Accessories

Expand the possibilities of single-well BioCAM systems.

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Created with Sketch.
Multi-Well
Created with Sketch.
Single-Well
Created with Sketch.
Software
Created with Sketch.
Accessories
3Brain's HyperCAM Alpha

HyperCAM Alpha

The 6-well CorePlate™-powered platform designed for both cell culture and tissue preparations.

Discover more
3Brain's CorePlate™ Multiwells

CorePlate™ Multiwells

The CorePlate™ technology’s processing capabilities convert the multiwell plates into smart objects.

Discover more
The only fully bi-directional HD-MEA (microelectrode array) platform for 2D and 3D in vitro electrophysiology.

BioCAM DupleX

The only fully bi-directional HD-MEA platform for 2D and 3D in-vitro electrophysiology.

Discover more
Our genuine HD-MEA (microelectrode array) platform with everything you need for in vitro neuronal physiology. - BioCAM X

BioCAM X

Our genuine high-end HD-MEA platform with everything you need for in-vitro neuron physiology.

Discover more

Single-Well HD-MEAs

A varied selection of high-density MEAs to match your precise research needs.

Discover more

BrainWave 5

The software that combines all you need to acquire, analyze and manage data from CorePlate™ multiwells.

Discover more

BrainWave 4

The companion of our single-well HD-MEAs to visualize, record, and analyze cell activity in real-time.

Discover more
IO Connector Box - 3Brain Accessories: featuring multiple modules for the CMOS-MEA channels

Single-Well Accessories

Expand the possibilities of the single-well BioCAM systems.

Discover more
Created with Sketch.
Multi-Well
Created with Sketch.
Single-Well
Created with Sketch.
Software
Created with Sketch.
Accessories
3Brain's HyperCAM Alpha

HyperCAM Alpha

The 6-well CorePlate™-powered platform designed for both cell culture and tissue preparations.

Discover more
3Brain's CorePlate™ Multiwells

CorePlate™ Multiwells

The CorePlate™ technology’s processing capabilities convert the multiwell plates into smart objects.

Discover more
The only fully bi-directional HD-MEA (microelectrode array) platform for 2D and 3D in vitro electrophysiology.

BioCAM DupleX

The only fully bi-directional HD-MEA platform for 2D and 3D in-vitro electrophysiology.

Discover more
BioCAM X - 3Brain

BioCAM X

Our genuine high-end HD-MEA platform with everything you need for in-vitro neuron physiology.

Discover more

Single-Well HD-MEAs

A varied selection of high-density MEAs to match your precise research needs.

Discover more
BrainWave 5

BrainWave 5

The software that combines all you need to acquire, analyze and manage data from CorePlate™ multiwells.

Discover more
BrainWave 4 - 3Brain

BrainWave 4

The companion of our single-well HD-MEAs to visualize, record, and analyze cell activity in real-time.

Discover more
IO Connector Box - 3Brain Accessories: featuring multiple modules for the CMOS-MEA channels

Single-Well Accessories

Expand the possibilities of the single-well BioCAM systems.

Discover more
Our Mission

3Brain strives to provide researchers with breakthrough technology to improve understanding of organs and related illnesses.

3Brain strives to provide researchers with breakthrough technology to improve the understanding of organs and their related illnesses.

How can 3Brain products boost your data?

From the bench to the paper

1

Simplifying experimental setups into an all-in-one compact design with the help of advanced, user-friendly acquisition and analysis software.

1

Simplifying experimental setups into an all-in-one compact design, including an advanced and user friendly acquisition and analysis software

See the BioCAM DupleX

2

Gaining a deeper understanding of neuronal networks using a sensitive technology that provides superior spatial and temporal resolution.

2

Getting a deeper understanding of neuronal networks using a sensitive technology providing a superior spatial and temporal resolution

See CorePlate™ technology

3

Obtaining clearer and more reliable statistics while requiring fewer experiments – all in a time-efficient manner.

3

Obtaining clearer and more reliable statistics while requiring less experiments - all in a time efficient manner

See latest publications

Resources

See our MEA neuro-imaging technology in action

Explore the capabilities of our neuron processors (also known as high density microelectrode arrays - HD-MEAs) and our software tools: take a look at these experimental data samples and download the free version of BrainWave.

DownloadsExamples

Latest News

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April 20, 2022

3Brain @ iPSZurich Symposium 2022

Interested in connecting your stem cells with a computer? We're at the iPSZurich Symposium today at the main building of the University of Zürich. Swing by before it ends and get a glimpse into the future of iPSC research with HD-MEA!

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June 15, 2022

3Brain @ ISSCR 2022

Join us at ISSCR 2022 this week at booth #837! We have tons to show on how our deep tech solutions will make your 2D & 3D iPSC research easy, elegant and smart. No matter if phenotype assessment, drug screening or discovery, our non-invasive functional assay tech is here to stay.

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June 1, 2022

3Brain @ The Cortical Development Conference 2022

We're at the Cortical Development Conference 2022 this Wednesday at 13:00! We have Marco Aquila presenting about our latest developments and also our new revolutionary 3D tech. Head over to check out how our brain-on-chip tech can simplify and empower your research in exciting ways. products are made with and for researchers.We'll also be at our booth for scientific discussions and more extensive application questions. Don't be shy, we love to talk about science

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Latest Publication

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Neuronal Cultures
Combined small molecule treatment accelerates timing of maturation in human pluripotent stem cell-derived neurons

Hergenreder E., Zorina Y., Zhao Z., Munguba H., Calder E.L., Baggiolini A., Minotti A.P., Walsh R.M., Liston C., Levitz J., Garippa R., Chen S., Ciceri G., and Studer L.

BioRXiv

Acute Brain Slices
Discovering Microcircuit Secrets With Multi-Spot Imaging and Electrophysiological Recordings: The Example of Cerebellar Network Dynamics

Tognolina M., Monteverdi A., and D'Angelo E.

Frontiers in Cellular Neuroscience (2022). DOI: 10.3389/fncel.2022.805670

Acute Retina
A novel approach to the functional classification of retinal ganglion cells

Hilgen G., Kartsaki E., Kartysh V., Cessac B. and Sernagor E.

Open Biol (2022). DOI: 0.1098/rsob.210367

Organoids
Human Retinal Organoids Provide a Suitable Tool for Toxicological Investigations: a Comprehensive Validation Using Drugs and Compounds Affecting the Retina

Dorgau B., Georgiou M., Chaudhary A., Moya-Molina M., Collin J., Queen R., Hilgen G., Davey T., Hewitt P., Schmitt M., Kustermann S., Pognan F., Steel D. H., Sernagor E., Armstrong L., and Lako M.

Stem Cells Transl Med. (2022). DOI: 10.1093/stcltm/szab010

Latest Publications

View all  
Neuronal Cultures
Combined small molecule treatment accelerates timing of maturation in human pluripotent stem cell-derived neurons

Hergenreder E., Zorina Y., Zhao Z., Munguba H., Calder E.L., Baggiolini A., Minotti A.P., Walsh R.M., Liston C., Levitz J., Garippa R., Chen S., Ciceri G., and Studer L.

BioRXiv

Acute Brain Slices
Discovering Microcircuit Secrets With Multi-Spot Imaging and Electrophysiological Recordings: The Example of Cerebellar Network Dynamics

Tognolina M., Monteverdi A., and D'Angelo E.

Frontiers in Cellular Neuroscience (2022). DOI: 10.3389/fncel.2022.805670

Acute Retina
A novel approach to the functional classification of retinal ganglion cells

Hilgen G., Kartsaki E., Kartysh V., Cessac B. and Sernagor E.

Open Biol (2022). DOI: 0.1098/rsob.210367

Organoids
Human Retinal Organoids Provide a Suitable Tool for Toxicological Investigations: a Comprehensive Validation Using Drugs and Compounds Affecting the Retina

Dorgau B., Georgiou M., Chaudhary A., Moya-Molina M., Collin J., Queen R., Hilgen G., Davey T., Hewitt P., Schmitt M., Kustermann S., Pognan F., Steel D. H., Sernagor E., Armstrong L., and Lako M.

Stem Cells Transl Med. (2022). DOI: 10.1093/stcltm/szab010

Neuronal Cultures

Hergenreder E., Zorina Y., Zhao Z., Munguba H., Calder E.L., Baggiolini A., Minotti A.P., Walsh R.M., Liston C., Levitz J., Garippa R., Chen S., Ciceri G., and Studer L.

BioRXiv

Acute Brain Slices

Veleanu M., Urrieta-Chávez B., Sigoillot S. M., and Selimi F.

PNAS (2022). DOI: 10.1073/pnas.2122544119

Acute Retina

Hilgen G., Kartsaki E., Kartysh V., Cessac B. and Sernagor E.

Open Biol (2022). DOI: 0.1098/rsob.210367

Organoids

Dorgau B., Georgiou M., Chaudhary A., Moya-Molina M., Collin J., Queen R., Hilgen G., Davey T., Hewitt P., Schmitt M., Kustermann S., Pognan F., Steel D. H., Sernagor E., Armstrong L., and Lako M.

Stem Cells Transl Med. (2022). DOI: 10.1093/stcltm/szab010

Do you want to know more? Book a chat or email us, as our neuroscientist team is here to assist you.
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