In-Plate Intelligence
Bringing you CorePlate™: the next-generation microelectrode array system for drug discovery and neuronal networks research
A cell-electronic interface for deep access of organoids and tissues
First-in-class 3D-CMOS chip for biomarker discovery, phenotypic screening and cellular assays.
Discover more
Discover more
The 3Brain - Massimo Grattarola Award applications has ended for 2022!
Thank you all for taking your time in applying for this year's Award. As we progress through the first round of evaluations, we will inform all 5 finalists at the beginning of September.
Follow us on Twitter or Linkedin, as we wait to see who will advance before the jury of this year!
HyperCAM Alpha
HyperCAM Alpha
CorePlate™ Multiwells
CorePlate™ Multiwells
HyperCAM Alpha
HyperCAM Alpha
CorePlate™ Multiwells
CorePlate™ Multiwells
Our Mission
3Brain strives to provide researchers with breakthrough technology to improve understanding of organs and related illnesses.
3Brain strives to provide researchers with breakthrough technology to improve the understanding of organs and their related illnesses.
How can 3Brain products boost your data?
From the bench to the paper
1
Simplifying experimental setups into an all-in-one compact design with the help of advanced, user-friendly acquisition and analysis software.
1
Simplifying experimental setups into an all-in-one compact design, including an advanced and user friendly acquisition and analysis software
See the BioCAM DupleX
2
Gaining a deeper understanding of neuronal networks using a sensitive technology that provides superior spatial and temporal resolution.
2
Getting a deeper understanding of neuronal networks using a sensitive technology providing a superior spatial and temporal resolution
See CorePlate™ technology
3
Obtaining clearer and more reliable statistics while requiring fewer experiments – all in a time-efficient manner.
3
Obtaining clearer and more reliable statistics while requiring less experiments - all in a time efficient manner
See latest publications
Resources
See our MEA neuro-imaging technology in action
Explore the capabilities of our neuron processors (also known as high density microelectrode arrays - HD-MEAs) and our software tools: take a look at these experimental data samples and download the free version of BrainWave.
Latest News
View all
New Publication: "Revealing directed effective connectivity of cortical neuronal networks from measurements"
Can scientists model in vitro neuronal culture as a stochastic dynamical system using spatio-temporal data from HD-MEA?
Tour de force to reconstruct network connectivity & dynamics of synapses by Sun C. et. al., from the Chinese University of Hong Kong, Shatin.
New Publication: "Receptivefield estimation in large visual neuron assemblies using a super-resolution approach"
Fascinating new method paper from Pamplona et al., using super-resolution principles and our CMOS-MEA to map the receptive fields of mouse retina from large heterogeneous neuronal populations with high fidelity.
New Publication: "Modified climbing fiber/Purkinje cell synaptic connectivity in the cerebellum of the neonatal phencyclidine model of schizophrenia"
How does drug abuse impact neural network remodeling during development?
Interesting paper from Veleanu et al. from (CNRS - Centre national de la recherche scientifique) using our CMOS-MEA to show neonatal PCP impacts connectivity, but causes no long-term difference in activity nor cytoarchitecture.
What’s a Rich Text element?
The rich text element allows you to create and format headings, paragraphs, blockquotes, images, and video all in one place instead of having to add and format them individually. Just double-click and easily create content.
Static and dynamic content editing
A rich text element can be used with static or dynamic content. For static content, just drop it into any page and begin editing. For dynamic content, add a rich text field to any collection and then connect a rich text element to that field in the settings panel. Voila!
How to customize formatting for each rich text
Headings, paragraphs, blockquotes, figures, images, and figure captions can all be styled after a class is added to the rich text element using the "When inside of" nested selector system.
Latest Publication
.svg)
Neuronal Cultures
Functional connectivity in in vitro neuronal assemblies
Frontiers (2015). DOI: 10.3389/fncir.2015.00057
Acute Brain Slices
Hypoxia induced carbonic anhydrase mediated dorsal horn neuron activation and induction of neuropathic pain
PAIN(2022). DOI: 10.1097/j.pain.0000000000002627
Acute Retina
Receptive field estimation in large visual neuron assemblies using a super-resolution approach
Journal of Neurophysiology (2022). DOI: 10.1152/jn.00076.2021
Organoids
Human Retinal Organoids Provide a Suitable Tool for Toxicological Investigations: a Comprehensive Validation Using Drugs and Compounds Affecting the Retina
Stem Cells Transl Med. (2022). DOI: 10.1093/stcltm/szab010
Latest Publications
Neuronal Cultures
Functional connectivity in in vitro neuronal assemblies
Frontiers (2015). DOI: 10.3389/fncir.2015.00057
Acute Brain Slices
Hypoxia induced carbonic anhydrase mediated dorsal horn neuron activation and induction of neuropathic pain
PAIN(2022). DOI: 10.1097/j.pain.0000000000002627
Acute Retina
Receptive field estimation in large visual neuron assemblies using a super-resolution approach
Journal of Neurophysiology (2022). DOI: 10.1152/jn.00076.2021
Organoids
Human Retinal Organoids Provide a Suitable Tool for Toxicological Investigations: a Comprehensive Validation Using Drugs and Compounds Affecting the Retina
Stem Cells Transl Med. (2022). DOI: 10.1093/stcltm/szab010
Neuronal Cultures
APS Physics (2022). DOI: 10.1103/PhysRevE.105.044406
Acute Brain Slices
Frontiers in Neuroscience (2022). DOI: 10.3389/fnins.2022.904931
Acute Retina
Receptive field estimation in large visual neuron assemblies using a super-resolution approach
(paper)
Journal of Neurophysiology (2022). DOI: 10.1152/jn.00076.2021
Organoids
Stem Cells Transl Med. (2022). DOI: 10.1093/stcltm/szab010
