In-Plate Intelligence

Bringing you CorePlate™: the next-generation microelectrode array system for drug discovery and neuronal networks research

The 3Brain Massimo Grattarola Award
00
DAYS
00
HOURS
00
MIN
00
SEC

Thank you to all applicants who applied for this year's 3Brain Massimo Grattarola Award!

And contragulations again to the winner, Dr. Martial Caillaud of the Université de Nantes.

Submit your email now to recieve a reminder ahead of time for the next award:

Thank you!
Email reminders will be sent out soon!
Oops! Something went wrong while submitting the form.

HyperCAM Alpha

Discover more

HyperCAM Alpha

Discover More

BioCAM DupleX

Discover more
3Brain's bidirectional single-well HD MEA - BioCAM DupleX

BioCAM DupleX

Discover More

HyperCAM Alpha

Discover more

HyperCAM Alpha

Discover More

CorePlate™ Multiwells

Discover more

CorePlate™ Multiwells

Discover More
Created with Sketch.
Multiwell
Created with Sketch.
Single-Well
Created with Sketch.
Software
Created with Sketch.
Accessories
HyperCAM Alpha - 3Brain

HyperCAM Alpha

The 6-well, CorePlate™-powered multi-well platform delivering high-resolution functional screening.

Discover more
CorePlate™ Multiwells - 3Brain

CorePlate™ Multiwells

CorePlate™ processing capabilities convert multi-well plates into smart objects.

Discover more
The only fully bi-directional HD-MEA (microelectrode array) platform for 2D and 3D in vitro electrophysiology.

BioCAM DupleX

The only fully bi-directional HD-MEA platformfor 2D and 3D in vitro electrophysiology.

Discover more
Our genuine HD-MEA (microelectrode array) platform with everything you need for in vitro neuronal physiology. - BioCAM X

BioCAM X

Our genuine HD-MEA platform with everything you need for in vitro neuronal network physiology.

Discover more
3Brain's Single-Well HD-MEAs

Single-Well HD-MEAs

A varied selection of high-density MEAs to match your precise research needs with the single-well devices.

Discover more
BrainWave 5

BrainWave 5

The software that combines all you need to acquire, analyze and manage data from CorePlate™ multi-wells.

Discover more
BrainWave 4 - 3Brain

BrainWave 4

The companion for our single-well HD-MEAs to visualize, record and analyze neural cell activity in real time.

Discover more
IO Connector Box - 3Brain Accessories: featuring multiple modules for the CMOS-MEA channels

Single-Well Accessories

Expand the possibilities of single-well BioCAM systems.

Discover more
Created with Sketch.
Multi-Well
Created with Sketch.
Single-Well
Created with Sketch.
Software
Created with Sketch.
Accessories
HyperCAM Alpha - 3Brain

HyperCAM Alpha

The 6-well CorePlate™-powered platform designed for both cell culture and tissue preparations.

Discover more
CorePlate™ Multiwells - 3Brain

CorePlate™ Multiwells

The CorePlate™ technology’s processing capabilities convert the multiwell plates into smart objects.

Discover more
The only fully bi-directional high density microelectrode array platform for 2D and 3D in vitro electrophysiology.

BioCAM DupleX

The only fully bi-directional HD-MEA platform for 2D and 3D in-vitro electrophysiology.

Discover more

BioCAM X

Our genuine high-end HD-MEA platform with everything you need for in-vitro neuron physiology.

Discover more

Single-Well HD-MEAs

A varied selection of high-density MEAs to match your precise research needs.

Discover more
BrainWave 5

BrainWave 5

The software that combines all you need to acquire, analyze and manage data from CorePlate™ multiwells.

Discover more
BrainWave 4 - 3Brain

BrainWave 4

The companion of our single-well HD-MEAs to visualize, record, and analyze cell activity in real-time.

Discover more
IO Connector Box - 3Brain Accessories: featuring multiple modules for the CMOS-MEA channels

Single-Well Accessories

Expand the possibilities of the single-well BioCAM systems.

Discover more
Created with Sketch.
Multi-Well
Created with Sketch.
Single-Well
Created with Sketch.
Software
Created with Sketch.
Accessories
HyperCAM Alpha - 3Brain

HyperCAM Alpha

The 6-well CorePlate™-powered platform designed for both cell culture and tissue preparations.

Discover more
CorePlate™ Multiwells - 3Brain

CorePlate™ Multiwells

The CorePlate™ technology’s processing capabilities convert the multiwell plates into smart objects.

Discover more
The only fully bi-directional high density microelectrode array platform for 2D and 3D in vitro electrophysiology.

BioCAM DupleX

The only fully bi-directional HD-MEA platform for 2D and 3D in-vitro electrophysiology.

Discover more
BioCAM X - 3Brain

BioCAM X

Our genuine high-end HD-MEA platform with everything you need for in-vitro neuron physiology.

Discover more
3Brain's Single-Well HD-MEAs

Single-Well HD-MEAs

A varied selection of high-density MEAs to match your precise research needs.

Discover more
BrainWave 5

BrainWave 5

The software that combines all you need to acquire, analyze and manage data from CorePlate™ multiwells.

Discover more
BrainWave 4 - 3Brain

BrainWave 4

The companion of our single-well HD-MEAs to visualize, record, and analyze cell activity in real-time.

Discover more
IO Connector Box - 3Brain Accessories: featuring multiple modules for the CMOS-MEA channels

Single-Well Accessories

Expand the possibilities of the single-well BioCAM systems.

Discover more
Our Mission

3Brain strives to provide researchers with breakthrough technology to improve understanding of organs and related illnesses.

3Brain strives to provide researchers with breakthrough technology to improve the understanding of organs and their related illnesses.

How can 3Brain products boost your data?

From the bench to the paper

1

Simplifying experimental setups into an all-in-one compact design with the help of advanced, user-friendly acquisition and analysis software.

1

Simplifying experimental setups into an all-in-one compact design, including an advanced and user friendly acquisition and analysis software

See the BioCAM DupleX

2

Gaining a deeper understanding of neuronal networks using a sensitive technology that provides superior spatial and temporal resolution.

2

Getting a deeper understanding of neuronal networks using a sensitive technology providing a superior spatial and temporal resolution

See CorePlate™ technology

3

Obtaining clearer and more reliable statistics while requiring fewer experiments – all in a time-efficient manner.

3

Obtaining clearer and more reliable statistics while requiring less experiments - all in a time efficient manner

See latest publications

Resources

See our MEA neuro-imaging technology in action

Explore the capabilities of our neuron processors (also known as high density microelectrode arrays - HD-MEAs) and our software tools: take a look at these experimental data samples and download the free version of BrainWave.

DownloadsExamples

Latest News

View all

May 7, 2021

New Publication: "A Monolayer System for the Efficient Generation of Motor Neuron Progenitors and Functional Motor Neurons from Human Pluripotent Stem Cells"

The success of your experiments relies highly on the generation of a robust, efficient and stable model. In this beautiful study from Cutarelli A. et al. (Università di Trento), the authors, faced with the limitations of current protocols for differentiating motor neurons from hiPSCs, have developed a new model optimized to convert hiPSCs into large quantities of functional MNs and their progenitors. Their results obtained with a 3Brain BioCAM system to assess neuronal network functionality are described in this paper.

See more
June 23, 2021

Welcome Dr. Andrew Thomas on our board of directors as Chairman.

3Brain would like to welcome Dr. Andrew Thomas on our board of directors as Chairman.

See more
June 21, 2021

3Brain @ ISSCR 2021

The ISSCR 2021 Annual meeting begins next week on the 21st of June!
We're excited to be sharing more information with you about the HyperCAM Alpha at our booth for all those interested in 3Brain's new CorePlate™ technology for stem cells, ipsc, disease modeling, drug discovery, research, and more!

Reach out to any of us during the event, we are looking forward to sharing with you about the HyperCAM Alpha and our CorePlate™ Technology!

See more

Latest Publication

View all
Neuronal Cultures
A Monolayer System for the Efficient Generation of Motor Neuron Progenitors and Functional Motor Neurons from Human Pluripotent Stem Cells

Cutarelli A., Martínez-Rojas V.A., Tata A., Battistella I., Rossi D., Arosio D., Musio C., and Conti L.

MDPI (2021). DOI: https://doi.org/10.3390/cells10051127

Acute Brain Slices
Sushi domain-containing protein 4 controls synaptic plasticity and motor learning

Gonzalez-Calvo I., Iyer K., Carquin M., Khayachi A., Giuliani F. A., Sigoillot S. M., Vincent J., Seveno M., Veleanu M., Tahraoui S., Albert M., Vigy O., Bosso-Lefevre C., Nadjar Y., Dumoulin A., Triller A., Bessereau J-L., Rondi-Reig L., Isope P., and Selimi F.

eLife (2021) DOI: https://doi.org/10.7554/eLife.65712

Acute Retina
Transplanted pluripotent stem cell‐derived photoreceptor precursors elicit conventional and unusual light responses in mice with advanced retinal degeneration

Zerti D., Hilgen G., Dorgau B., Collin J., Ader M., Armstrong L., Sernagor E., and Lako M.

Stem Cells Journal (2021). DOI: https://doi.org/10.1002/stem.3365

Organoids
Human derived cortical excitatory neurospheroids showed spontaneous activity on micro electrodes array

L. Muzzi, M. Falappa, A. Maccione, D. di Lisa, M. Frega, and S. Martinoia.

IEEE (2021) DOI: 10.1109/NER49283.2021.9441261

Latest Publications

View all  
Neuronal Cultures
A Monolayer System for the Efficient Generation of Motor Neuron Progenitors and Functional Motor Neurons from Human Pluripotent Stem Cells

Cutarelli A., Martínez-Rojas V.A., Tata A., Battistella I., Rossi D., Arosio D., Musio C., and Conti L.

MDPI (2021). DOI: https://doi.org/10.3390/cells10051127

Acute Brain Slices
Sushi domain-containing protein 4 controls synaptic plasticity and motor learning

Gonzalez-Calvo I., Iyer K., Carquin M., Khayachi A., Giuliani F. A., Sigoillot S. M., Vincent J., Seveno M., Veleanu M., Tahraoui S., Albert M., Vigy O., Bosso-Lefevre C., Nadjar Y., Dumoulin A., Triller A., Bessereau J-L., Rondi-Reig L., Isope P., and Selimi F.

eLife (2021) DOI: https://doi.org/10.7554/eLife.65712

Acute Retina
Transplanted pluripotent stem cell‐derived photoreceptor precursors elicit conventional and unusual light responses in mice with advanced retinal degeneration

Zerti D., Hilgen G., Dorgau B., Collin J., Ader M., Armstrong L., Sernagor E., and Lako M.

Stem Cells Journal (2021). DOI: https://doi.org/10.1002/stem.3365

Organoids
Human derived cortical excitatory neurospheroids showed spontaneous activity on micro electrodes array

L. Muzzi, M. Falappa, A. Maccione, D. di Lisa, M. Frega, and S. Martinoia.

IEEE (2021) DOI: 10.1109/NER49283.2021.9441261

Neuronal Cultures

Cutarelli A., Martínez-Rojas V.A., Tata A., Battistella I., Rossi D., Arosio D., Musio C., and Conti L.

MDPI (2021). DOI: https://doi.org/10.3390/cells10051127

Acute Brain Slices

Gonzalez-Calvo I., Iyer K., Carquin M., Khayachi A., Giuliani F. A., Sigoillot S. M., Vincent J., Seveno M., Veleanu M., Tahraoui S., Albert M., Vigy O., Bosso-Lefevre C., Nadjar Y., Dumoulin A., Triller A., Bessereau J-L., Rondi-Reig L., Isope P., and Selimi F.

eLife (2021) DOI: https://doi.org/10.7554/eLife.65712

Acute Retina

Zerti D., Hilgen G., Dorgau B., Collin J., Ader M., Armstrong L., Sernagor E., and Lako M.

Stem Cells Journal (2021). DOI: https://doi.org/10.1002/stem.3365

Organoids

L. Muzzi, M. Falappa, A. Maccione, D. di Lisa, M. Frega, and S. Martinoia.

IEEE (2021) DOI: 10.1109/NER49283.2021.9441261

Our neuroscientist team is here to assist you with your application needs with our products.
Contact Us