In-Plate Intelligence
Bringing you CorePlate™: the next-generation microelectrode array system for drug discovery and neuronal networks research
A cell-electronic interface for deep access of organoids and tissues
First-in-class 3D-CMOS chip for biomarker discovery, phenotypic screening and cellular assays.
Discover more
Discover more
The 3Brain - Massimo Grattarola Award applications has ended for 2022!
Thank you all for taking your time in applying for this year's Award. As we progress through the first round of evaluations, we will inform all 5 finalists at the beginning of September.
Follow us on Twitter or Linkedin, as we wait to see who will advance before the jury of this year!
HyperCAM Alpha
HyperCAM Alpha
CorePlate™ Multiwells
CorePlate™ Multiwells
HyperCAM Alpha
HyperCAM Alpha
CorePlate™ Multiwells
CorePlate™ Multiwells
Our Mission
3Brain strives to provide researchers with breakthrough technology to improve understanding of organs and related illnesses.
3Brain strives to provide researchers with breakthrough technology to improve the understanding of organs and their related illnesses.
How can 3Brain products boost your data?
From the bench to the paper
1
Simplifying experimental setups into an all-in-one compact design with the help of advanced, user-friendly acquisition and analysis software.
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Simplifying experimental setups into an all-in-one compact design, including an advanced and user friendly acquisition and analysis software
See the BioCAM DupleX
2
Gaining a deeper understanding of neuronal networks using a sensitive technology that provides superior spatial and temporal resolution.
2
Getting a deeper understanding of neuronal networks using a sensitive technology providing a superior spatial and temporal resolution
See CorePlate™ technology
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Obtaining clearer and more reliable statistics while requiring fewer experiments – all in a time-efficient manner.
3
Obtaining clearer and more reliable statistics while requiring less experiments - all in a time efficient manner
See latest publications
Resources
See our MEA neuro-imaging technology in action
Explore the capabilities of our neuron processors (also known as high density microelectrode arrays - HD-MEAs) and our software tools: take a look at these experimental data samples and download the free version of BrainWave.
Latest News
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3Brain @ Conference on Advancements in Organoid Sciences
Brain organoids hold so much promise for the future of pre-clinical research & drug discovery, but how can we access their complexity?
Visit our poster at CAOS (MSH Medical School Hamburg): functional & network activity in 5-month-old brain organoids with our 3D biointerface technology!
PIN - Research Pulse:
How does the environment shape neuronal information processing in the retina? And what does the time of the day have to do with it?
Apparently, quite a lot. For morning birds and night owls alike. Read more in this month's blog post!
PIN - Research Pulse: Pressure point: Neuron
A new research pulse blog is out!
This month, we look at mechanobiology, and how the physical properties of the brain impact neuronal activity.
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Latest Publication
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Neuronal Cultures
Functional connectivity in in vitro neuronal assemblies
Frontiers (2015). DOI: 10.3389/fncir.2015.00057
Acute Brain Slices
Hypoxia induced carbonic anhydrase mediated dorsal horn neuron activation and induction of neuropathic pain
PAIN(2022). DOI: 10.1097/j.pain.0000000000002627
Acute Retina
Glial Bmal1 role in mammalian retina daily changes
Scientific Reports (2022). DOI: 10.1038/s41598-022-25783-1
Organoids
Incorporating microglia-like cells in human induced pluripotent stem cell-derived retinal organoids
Journal of Cellcular and Molecular Medicine (2023). DOI: 10.1111/jcmm.17670
Latest Publications
Neuronal Cultures
Functional connectivity in in vitro neuronal assemblies
Frontiers (2015). DOI: 10.3389/fncir.2015.00057
Acute Brain Slices
Hypoxia induced carbonic anhydrase mediated dorsal horn neuron activation and induction of neuropathic pain
PAIN(2022). DOI: 10.1097/j.pain.0000000000002627
Acute Retina
Glial Bmal1 role in mammalian retina daily changes
Scientific Reports (2022). DOI: 10.1038/s41598-022-25783-1
Organoids
Incorporating microglia-like cells in human induced pluripotent stem cell-derived retinal organoids
Journal of Cellcular and Molecular Medicine (2023). DOI: 10.1111/jcmm.17670
Neuronal Cultures
APS Physics (2022). DOI: 10.1103/PhysRevE.105.044406
Acute Brain Slices
Frontiers in Neuroscience (2022). DOI: 10.3389/fnins.2022.904931
Acute Retina
Scientific Reports (2022). DOI: 10.1038/s41598-022-25783-1
Organoids
Incorporating microglia-like cells in human induced pluripotent stem cell-derived retinal organoids
(paper)
Journal of Cellcular and Molecular Medicine (2023). DOI: 10.1111/jcmm.17670
