In-Plate Intelligence

Bringing you CorePlate™: the next-generation microelectrode array system for drug discovery and neuronal networks research

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The 3Brain - Massimo Grattarola Award has begun for 2022!

The Award aims to support young researchers into the start of their career. The winner will be awarded €15,000.

Head in to review the conditions and begin your application!

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Submit your email now to recieve a reminder ahead of time for the next award:

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HyperCAM Alpha

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HyperCAM Alpha

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CorePlate™ Multiwells

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CorePlate™ Multiwells

CorePlate™ Multiwells

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HyperCAM Alpha

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HyperCAM Alpha

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CorePlate™ Multiwells

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CorePlate™ Multiwells

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Multiwell
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Single-Well
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Software
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Accessories
HyperCAM Alpha - 3Brain

HyperCAM Alpha

The 6-well, CorePlate™-powered multi-well platform delivering high-resolution functional screening.

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CorePlate™ Multiwells - 3Brain

CorePlate™ Multiwells

CorePlate™ processing capabilities convert multi-well plates into smart objects.

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The only fully bi-directional HD-MEA (microelectrode array) platform for 2D and 3D in vitro electrophysiology.

BioCAM DupleX

The only fully bi-directional HD-MEA platformfor 2D and 3D in vitro electrophysiology.

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Our genuine HD-MEA (microelectrode array) platform with everything you need for in vitro neuronal physiology. - BioCAM X

BioCAM X

Our genuine HD-MEA platform with everything you need for in vitro neuronal network physiology.

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3Brain's Single-Well HD-MEAs

Single-Well HD-MEAs

A varied selection of high-density MEAs to match your precise research needs with the single-well devices.

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BrainWave 5

The software that combines all you need to acquire, analyze and manage data from CorePlate™ multi-wells.

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BrainWave 4 - 3Brain

BrainWave 4

The companion for our single-well HD-MEAs to visualize, record and analyze neural cell activity in real time.

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IO Connector Box - 3Brain Accessories: featuring multiple modules for the CMOS-MEA channels

Single-Well Accessories

Expand the possibilities of single-well BioCAM systems.

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Created with Sketch.
Multi-Well
Created with Sketch.
Single-Well
Created with Sketch.
Software
Created with Sketch.
Accessories
HyperCAM Alpha - 3Brain

HyperCAM Alpha

The 6-well CorePlate™-powered platform designed for both cell culture and tissue preparations.

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CorePlate™ Multiwells - 3Brain

CorePlate™ Multiwells

The CorePlate™ technology’s processing capabilities convert the multiwell plates into smart objects.

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The only fully bi-directional high density microelectrode array platform for 2D and 3D in vitro electrophysiology.

BioCAM DupleX

The only fully bi-directional HD-MEA platform for 2D and 3D in-vitro electrophysiology.

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BioCAM X

Our genuine high-end HD-MEA platform with everything you need for in-vitro neuron physiology.

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Single-Well HD-MEAs

A varied selection of high-density MEAs to match your precise research needs.

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BrainWave 5

BrainWave 5

The software that combines all you need to acquire, analyze and manage data from CorePlate™ multiwells.

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BrainWave 4 - 3Brain

BrainWave 4

The companion of our single-well HD-MEAs to visualize, record, and analyze cell activity in real-time.

Discover more
IO Connector Box - 3Brain Accessories: featuring multiple modules for the CMOS-MEA channels

Single-Well Accessories

Expand the possibilities of the single-well BioCAM systems.

Discover more
Created with Sketch.
Multi-Well
Created with Sketch.
Single-Well
Created with Sketch.
Software
Created with Sketch.
Accessories
HyperCAM Alpha - 3Brain

HyperCAM Alpha

The 6-well CorePlate™-powered platform designed for both cell culture and tissue preparations.

Discover more
CorePlate™ Multiwells - 3Brain

CorePlate™ Multiwells

The CorePlate™ technology’s processing capabilities convert the multiwell plates into smart objects.

Discover more
The only fully bi-directional high density microelectrode array platform for 2D and 3D in vitro electrophysiology.

BioCAM DupleX

The only fully bi-directional HD-MEA platform for 2D and 3D in-vitro electrophysiology.

Discover more
BioCAM X - 3Brain

BioCAM X

Our genuine high-end HD-MEA platform with everything you need for in-vitro neuron physiology.

Discover more

Single-Well HD-MEAs

A varied selection of high-density MEAs to match your precise research needs.

Discover more
BrainWave 5

BrainWave 5

The software that combines all you need to acquire, analyze and manage data from CorePlate™ multiwells.

Discover more
BrainWave 4 - 3Brain

BrainWave 4

The companion of our single-well HD-MEAs to visualize, record, and analyze cell activity in real-time.

Discover more
IO Connector Box - 3Brain Accessories: featuring multiple modules for the CMOS-MEA channels

Single-Well Accessories

Expand the possibilities of the single-well BioCAM systems.

Discover more
Our Mission

3Brain strives to provide researchers with breakthrough technology to improve understanding of organs and related illnesses.

3Brain strives to provide researchers with breakthrough technology to improve the understanding of organs and their related illnesses.

How can 3Brain products boost your data?

From the bench to the paper

1

Simplifying experimental setups into an all-in-one compact design with the help of advanced, user-friendly acquisition and analysis software.

1

Simplifying experimental setups into an all-in-one compact design, including an advanced and user friendly acquisition and analysis software

See the BioCAM DupleX

2

Gaining a deeper understanding of neuronal networks using a sensitive technology that provides superior spatial and temporal resolution.

2

Getting a deeper understanding of neuronal networks using a sensitive technology providing a superior spatial and temporal resolution

See CorePlate™ technology

3

Obtaining clearer and more reliable statistics while requiring fewer experiments – all in a time-efficient manner.

3

Obtaining clearer and more reliable statistics while requiring less experiments - all in a time efficient manner

See latest publications

Resources

See our MEA neuro-imaging technology in action

Explore the capabilities of our neuron processors (also known as high density microelectrode arrays - HD-MEAs) and our software tools: take a look at these experimental data samples and download the free version of BrainWave.

DownloadsExamples

Latest News

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March 19, 2022

New Publication: "Non-Linear Frequency Dependence of Neurovascular Coupling in the Cerebellar Cortex Implies Vasodilation–Vasoconstriction Competition"

HD-MEA recordings of neuronal activity by Giuseppe Gagliano et al. from the University of Pavia, Italy help uncover a non-linear frequency dependence regulating competition between NO and 20-HETE.

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April 9, 2022

New Publication: "A novel approach to the functional classification of retinal ganglion cells"

Retinal ganglion cell functional classification is a key step in understanding visual processing and features extraction.Have a look at this new multimodal approach combining pharmacogenetics, immunisto chemistry and obviously large-scale activity recordings from our HD-MEAs!

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February 19, 2022

New Publication: "Human Retinal Organoids Provide a Suitable Tool for Toxicological Investigations: A Comprehensive Validation Using Drugs and Compounds Affecting the Retina"

In this paper by Dorgau B. et al of Newcastle University, retinal organoids were tested with well-known toxic compounds showing functional impairment similar to what is obtained in vivo. Read more into how organoids can effectively be used for in vitro toxicological studies through this paper.

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Latest Publication

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Neuronal Cultures
Revealing directed effective connectivity of cortical neuronal networks from measurements

Sun C., Lin K.C., Yeung Y., Ching E.S.C., Huang Y., Lai P., and Chan C.K.

APS Physics (2022). DOI: 10.1103/PhysRevE.105.044406

Acute Brain Slices
Non-Linear Frequency Dependence of Neurovascular Coupling in the Cerebellar Cortex Implies Vasodilation–Vasoconstriction Competition

Gagliano G., Monteverdi A., Casali S., Laforenza U., Gandini Wheeler-Kingshott C.A.M., D'Angelo E., and Mapelli L.

Cells (2022). DOI: 10.3390/cells11061047

Acute Retina
A novel approach to the functional classification of retinal ganglion cells

Hilgen G., Kartsaki E., Kartysh V., Cessac B. and Sernagor E.

Open Biol (2022). DOI: 0.1098/rsob.210367

Organoids
Human Retinal Organoids Provide a Suitable Tool for Toxicological Investigations: a Comprehensive Validation Using Drugs and Compounds Affecting the Retina

Dorgau B., Georgiou M., Chaudhary A., Moya-Molina M., Collin J., Queen R., Hilgen G., Davey T., Hewitt P., Schmitt M., Kustermann S., Pognan F., Steel D. H., Sernagor E., Armstrong L., and Lako M.

Stem Cells Transl Med. (2022). DOI: 10.1093/stcltm/szab010

Latest Publications

View all  
Neuronal Cultures
Revealing directed effective connectivity of cortical neuronal networks from measurements

Sun C., Lin K.C., Yeung Y., Ching E.S.C., Huang Y., Lai P., and Chan C.K.

APS Physics (2022). DOI: 10.1103/PhysRevE.105.044406

Acute Brain Slices
Non-Linear Frequency Dependence of Neurovascular Coupling in the Cerebellar Cortex Implies Vasodilation–Vasoconstriction Competition

Gagliano G., Monteverdi A., Casali S., Laforenza U., Gandini Wheeler-Kingshott C.A.M., D'Angelo E., and Mapelli L.

Cells (2022). DOI: 10.3390/cells11061047

Acute Retina
A novel approach to the functional classification of retinal ganglion cells

Hilgen G., Kartsaki E., Kartysh V., Cessac B. and Sernagor E.

Open Biol (2022). DOI: 0.1098/rsob.210367

Organoids
Human Retinal Organoids Provide a Suitable Tool for Toxicological Investigations: a Comprehensive Validation Using Drugs and Compounds Affecting the Retina

Dorgau B., Georgiou M., Chaudhary A., Moya-Molina M., Collin J., Queen R., Hilgen G., Davey T., Hewitt P., Schmitt M., Kustermann S., Pognan F., Steel D. H., Sernagor E., Armstrong L., and Lako M.

Stem Cells Transl Med. (2022). DOI: 10.1093/stcltm/szab010

Neuronal Cultures

Sun C., Lin K.C., Yeung Y., Ching E.S.C., Huang Y., Lai P., and Chan C.K.

APS Physics (2022). DOI: 10.1103/PhysRevE.105.044406

Acute Brain Slices

Gagliano G., Monteverdi A., Casali S., Laforenza U., Gandini Wheeler-Kingshott C.A.M., D'Angelo E., and Mapelli L.

Cells (2022). DOI: 10.3390/cells11061047

Acute Retina

Hilgen G., Kartsaki E., Kartysh V., Cessac B. and Sernagor E.

Open Biol (2022). DOI: 0.1098/rsob.210367

Organoids

Dorgau B., Georgiou M., Chaudhary A., Moya-Molina M., Collin J., Queen R., Hilgen G., Davey T., Hewitt P., Schmitt M., Kustermann S., Pognan F., Steel D. H., Sernagor E., Armstrong L., and Lako M.

Stem Cells Transl Med. (2022). DOI: 10.1093/stcltm/szab010

Have any questions? Book a chat or email us, as our neuroscientist team is here to assist you.
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