A cell-electronic interface for deep access of organoids and tissues
First-in-class 3D-CMOS chip for biomarker discovery, phenotypic screening and cellular assays.
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We are delighted to announce that Dr. Rahel Kastli, a postdoctoral researcher at Harvard University, has been awarded with the 2023 Massimo Grattarola Award!
Follow us on Twitter and LinkedIn for any updates.
HyperCAM Alpha
HyperCAM Alpha

CorePlate™ Multiwells

CorePlate™ Multiwells

HyperCAM Alpha
HyperCAM Alpha

CorePlate™ Multiwells
CorePlate™ Multiwells


Our Mission
3Brain strives to provide researchers with breakthrough technology to improve understanding of organs and related illnesses.
3Brain strives to provide researchers with breakthrough technology to improve the understanding of organs and their related illnesses.
How can 3Brain products boost your data?
From the bench to the paper
1
Simplifying experimental setups into an all-in-one compact design with the help of advanced, user-friendly acquisition and analysis software.
1
Simplifying experimental setups into an all-in-one compact design, including an advanced and user friendly acquisition and analysis software
See the BioCAM DupleX
2
Gaining a deeper understanding of neuronal networks using a sensitive technology that provides superior spatial and temporal resolution.
2
Getting a deeper understanding of neuronal networks using a sensitive technology providing a superior spatial and temporal resolution
See CorePlate™ technology
3
Obtaining clearer and more reliable statistics while requiring fewer experiments – all in a time-efficient manner.
3
Obtaining clearer and more reliable statistics while requiring less experiments - all in a time efficient manner
See latest publications
Resources
See our MEA neuro-imaging technology in action
Explore the capabilities of our neuron processors (also known as high density microelectrode arrays - HD-MEAs) and our software tools: take a look at these experimental data samples and download the free version of BrainWave.
Latest News
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3Brain @SLAS23
We're back at SLAS23 this year with some major 3D innovations!
Our microchip-based biointerface technology empowers researchers to explore intelligent biological networks like #brain organoids by linking them to information technology.
Booth #830. The future awaits.

3Brain @ Conference on Advancements in Organoid Sciences
Brain organoids hold so much promise for the future of pre-clinical research & drug discovery, but how can we access their complexity?
Visit our poster at CAOS (MSH Medical School Hamburg): functional & network activity in 5-month-old brain organoids with our 3D biointerface technology!

PIN - Research Pulse: Timekeeper: Glia?
How does the environment shape neuronal information processing in the retina? And what does the time of the day have to do with it?
Apparently, quite a lot. For morning birds and night owls alike. Read more in this month's blog post!

What’s a Rich Text element?
The rich text element allows you to create and format headings, paragraphs, blockquotes, images, and video all in one place instead of having to add and format them individually. Just double-click and easily create content.
Static and dynamic content editing
A rich text element can be used with static or dynamic content. For static content, just drop it into any page and begin editing. For dynamic content, add a rich text field to any collection and then connect a rich text element to that field in the settings panel. Voila!
How to customize formatting for each rich text
Headings, paragraphs, blockquotes, figures, images, and figure captions can all be styled after a class is added to the rich text element using the "When inside of" nested selector system.

Latest Publication

Neuronal Cultures
Neuronal network activity and connectivity are impaired in a conditional knockout mouse model with PCDH19 mosaic expression
Mol Psychiatry (2023). DOI: 10.1038/s41380-023-02022-1
Acute Brain Slices
Lipid-accumulated reactive astrocytes promote disease progression in epilepsy
Nature Neuroscience (2023). DOI: 10.1038/s41593-023-01288-6
Acute Retina
Birds multiplex spectral and temporal visual information via retinal On- and Off-channels
Nature Communications (2023). DOI: 10.1038/s41467-023-41032-z
Organoids
Decellularised extracellular matrix-derived peptides from neural retina and retinal pigment epithelium enhance the expression of synaptic markers and light responsiveness of human pluripotent stem cell derived retinal organoids
Science Direct (2019) DOI: 10.1016/j.biomaterials.2019.01.028
Latest Publications

Neuronal Cultures
Neuronal network activity and connectivity are impaired in a conditional knockout mouse model with PCDH19 mosaic expression
Mol Psychiatry (2023). DOI: 10.1038/s41380-023-02022-1

Acute Brain Slices
Lipid-accumulated reactive astrocytes promote disease progression in epilepsy
Nature Neuroscience (2023). DOI: 10.1038/s41593-023-01288-6

Acute Retina
Birds multiplex spectral and temporal visual information via retinal On- and Off-channels
Nature Communications (2023). DOI: 10.1038/s41467-023-41032-z

Organoids
Decellularised extracellular matrix-derived peptides from neural retina and retinal pigment epithelium enhance the expression of synaptic markers and light responsiveness of human pluripotent stem cell derived retinal organoids
Science Direct (2019) DOI: 10.1016/j.biomaterials.2019.01.028
Neuronal Cultures
Int. J. Mol. Sci. (2023) DOI: 10.3390/ijms241814064
Acute Brain Slices
Biomedicines (2023). DOI: 10.3390/biomedicines11051475
Acute Retina
Nature Communications (2023). DOI: 10.1038/s41467-023-41032-z
Organoids
Bioengineering (2023) DOI: 10.3390/bioengineering10040449