We strive to provide researchers with breakthrough technology to improve the understanding of organs such as the brain and heart and their related illnesses.


Microelectrode arrays (MEA) meet CMOS technology

Our disruptive microelectrode array, also known as multielectrode array (MEA), technology revolutionizes brain research by enabling a deeper investigation of neuronal networks. Our pioneering work with CMOS technology has allowed researchers to visualize signal propagations between thousands of cells at a sub-millisecond scale for the first time.

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Extend your possibilities in drug discovery and brain research

By collecting high-resolution electrophysiological data from neurons, cardiac cells, brain organoids, and human-derived stem cells, our microelectrode array (multielectrode array) technology opens up new possibilities in drug discovery by enabling functional imaging assays, the identification of network functional and dysfunctional states and the precise evaluation of pharmacological responses.

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High-resolution electrophysiology platforms

Explore our full line of microelectrode arrays, also known as multielectrode arrays (MEAs), our solution to your experimental needs.

BioCAM DupleX

BioCAM DupleX

The Next generation of in vitro HD-MEA systems

Fully redesigned to provide the most complete experience with high-density MEA technologies, BioCAM DupleX introduces a new standard in electrophysiology. Thousands of bi-directional electrodes to have the full control of your experiments.

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Discover a new dimension with high-resolution in vitro electrophysiology

Stemming from more than 10 years of development, our high-resolution CMOS-MEA system combines the latest integrated circuit computing performance with a durable and compact design.

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Unleash the power of your neuronal preparations

High density microelectrode arrays (HD-MEAs) featuring 4096 simultaneous readout channels and 16 stimulation sites arranged in different configurations meeting various experimental needs.

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Microelectrode Array accessory


Take your research further with customized accessories

Designed to fit our HD-MEA platforms, our accessories take your research in drug discovery, brain organoids, neuronal networks, and human-derived stem cells to the next level.

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Gathering high-resolution electrophysiological data has never been easier

Our advanced acquisition and analysis software is designed to manage dense electrophysiological data sets. BrainWave facilitates real-time visualization and the extraction of key metrics from high-density microelectrode array, or multielectrode array (HD-MEA), chips.

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See our microelectrode array technology in action

Explore the capabilities of our high-density microelectrode arrays, also known as multielectrode arrays (HD-MEAs), and software tools by taking a look at these experimental examples and downloading the latest version of BrainWave.

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Latest publications

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dissociated cultures

Transfer Entropy Based Connectivity Estimation of Spontaneously Firing Hippocampal Cultures on Multi Electrode Arraysconf. proc.

Lama N., Hargreaves A.J., Stevens B., Mcginnity T.M.


acute brain slices

Neuronal Glutamatergic Network Electrically Wired with Silent But Activatable Gap Junctionspaper

Ixmatlahua D. J., Vizcarra B., Gómez-Lira G., Romero-Maldonado I., Ortiz F., Rojas-Piloni G., Gutiérrez R.

The Journal of Neuroscience, 10 June 2020; DOI:https://doi.org/10.1523/JNEUROSCI.2590-19.2020

acute retina

Electrical Coupling of Heterotypic Ganglion Cells in the Mammalian Retinapaper

Christian Puller, Sabrina Duda, Elaheh Lotfi, Yousef Arzhangnia, Christoph T. Block, Malte T. Ahlers and Martin Greschner 

Journal of Neuroscience 5 February 2020, 40 (6) 1302-1310; DOI: https://doi.org/10.1523/JNEUROSCI.1374-19.2019


Jun 10 2020

Neuronal Glutamatergic Network Electrically Wired with Silent But Activatable Gap Junctions

New paper released! Beautiful work from Diana Ixmatlahua et al (Rafael Gutiérrez team, Center for Research and Advanced Studies of the National Polytechnic Institute, (Centro de Investigación y de Estudios Avanzados del IPN) Mexico). With the simultaneous recording of thousands of cells on a 3Brain HD-MEA, they discovered that the well-known glutamatergic mossy fiber synapse of the hippocampus was hiding silent but ready-to-use, pH-sensitive, electrical synapses.

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Mar 16 2020

3Brain during COVID-19

We would like to provide an update on 3Brain AG, especially after the press conference held by the Federal Council last Friday.

Due to the events of COVID-19 in Switzerland. We would like to inform and ensure everyone on 3Brain's flow of operations as we will continue to stick to our commitments to our customers. Events will be ensured as far as we can and we will update all personnel by email for any changes ahead of time to avoid inconveniences on your behalf.

If you do have any inquiries, please feel free to get in contact directly with us at: info@3brain.com

Jan 30 2020

3Brain @ Neurex 2020

We attended Neurex's first workshop of 2020. With Dr.Sercan Deniz, in Strasbourg, meeting up with many others in the neuroscientific field over the theme of the "Cerebellum".

Jan 24 2020

3Brain @ SLAS2020

One of our first conferences into 2020!

Showing the true potentials of HD-MEAs as to how we bring CMOS technology together with MEAs. Displaying not only the BioCAM DupleX, but also the upcoming BioCAM MultipleX!