In-Plate Intelligence

Bringing you CorePlate™: the next-generation microelectrode array system for drug discovery and neuronal networks research

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The 3Brain - Massimo Grattarola Award has begun for 2022!

The Award aims to support younginto the start of their career. The winner will be awarded €15,000 after the final decision of the reviewing committee, around the mid of September this year.

Head into the page to review the conditions and begin your application before the deadline!

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Submit your email now to recieve a reminder ahead of time for the next award:

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HyperCAM Alpha

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HyperCAM Alpha

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CorePlate™ Multiwells

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3Brain's bidirectional single-well HD MEA - BioCAM DupleX

BioCAM DupleX

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HyperCAM Alpha

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HyperCAM Alpha

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CorePlate™ Multiwells

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CorePlate™ Multiwells

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Multiwell
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Single-Well
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Software
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Accessories
HyperCAM Alpha - 3Brain

HyperCAM Alpha

The 6-well, CorePlate™-powered multi-well platform delivering high-resolution functional screening.

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CorePlate™ Multiwells - 3Brain

CorePlate™ Multiwells

CorePlate™ processing capabilities convert multi-well plates into smart objects.

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The only fully bi-directional HD-MEA (microelectrode array) platform for 2D and 3D in vitro electrophysiology.

BioCAM DupleX

The only fully bi-directional HD-MEA platformfor 2D and 3D in vitro electrophysiology.

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Our genuine HD-MEA (microelectrode array) platform with everything you need for in vitro neuronal physiology. - BioCAM X

BioCAM X

Our genuine HD-MEA platform with everything you need for in vitro neuronal network physiology.

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3Brain's Single-Well HD-MEAs

Single-Well HD-MEAs

A varied selection of high-density MEAs to match your precise research needs with the single-well devices.

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BrainWave 5

The software that combines all you need to acquire, analyze and manage data from CorePlate™ multi-wells.

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BrainWave 4 - 3Brain

BrainWave 4

The companion for our single-well HD-MEAs to visualize, record and analyze neural cell activity in real time.

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IO Connector Box - 3Brain Accessories: featuring multiple modules for the CMOS-MEA channels

Single-Well Accessories

Expand the possibilities of single-well BioCAM systems.

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Created with Sketch.
Multi-Well
Created with Sketch.
Single-Well
Created with Sketch.
Software
Created with Sketch.
Accessories
HyperCAM Alpha - 3Brain

HyperCAM Alpha

The 6-well CorePlate™-powered platform designed for both cell culture and tissue preparations.

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CorePlate™ Multiwells - 3Brain

CorePlate™ Multiwells

The CorePlate™ technology’s processing capabilities convert the multiwell plates into smart objects.

Discover more
The only fully bi-directional high density microelectrode array platform for 2D and 3D in vitro electrophysiology.

BioCAM DupleX

The only fully bi-directional HD-MEA platform for 2D and 3D in-vitro electrophysiology.

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BioCAM X

Our genuine high-end HD-MEA platform with everything you need for in-vitro neuron physiology.

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Single-Well HD-MEAs

A varied selection of high-density MEAs to match your precise research needs.

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BrainWave 5

BrainWave 5

The software that combines all you need to acquire, analyze and manage data from CorePlate™ multiwells.

Discover more
BrainWave 4 - 3Brain

BrainWave 4

The companion of our single-well HD-MEAs to visualize, record, and analyze cell activity in real-time.

Discover more
IO Connector Box - 3Brain Accessories: featuring multiple modules for the CMOS-MEA channels

Single-Well Accessories

Expand the possibilities of the single-well BioCAM systems.

Discover more
Created with Sketch.
Multi-Well
Created with Sketch.
Single-Well
Created with Sketch.
Software
Created with Sketch.
Accessories
HyperCAM Alpha - 3Brain

HyperCAM Alpha

The 6-well CorePlate™-powered platform designed for both cell culture and tissue preparations.

Discover more
CorePlate™ Multiwells - 3Brain

CorePlate™ Multiwells

The CorePlate™ technology’s processing capabilities convert the multiwell plates into smart objects.

Discover more
The only fully bi-directional high density microelectrode array platform for 2D and 3D in vitro electrophysiology.

BioCAM DupleX

The only fully bi-directional HD-MEA platform for 2D and 3D in-vitro electrophysiology.

Discover more
BioCAM X - 3Brain

BioCAM X

Our genuine high-end HD-MEA platform with everything you need for in-vitro neuron physiology.

Discover more

Single-Well HD-MEAs

A varied selection of high-density MEAs to match your precise research needs.

Discover more
BrainWave 5

BrainWave 5

The software that combines all you need to acquire, analyze and manage data from CorePlate™ multiwells.

Discover more
BrainWave 4 - 3Brain

BrainWave 4

The companion of our single-well HD-MEAs to visualize, record, and analyze cell activity in real-time.

Discover more
IO Connector Box - 3Brain Accessories: featuring multiple modules for the CMOS-MEA channels

Single-Well Accessories

Expand the possibilities of the single-well BioCAM systems.

Discover more
Our Mission

3Brain strives to provide researchers with breakthrough technology to improve understanding of organs and related illnesses.

3Brain strives to provide researchers with breakthrough technology to improve the understanding of organs and their related illnesses.

How can 3Brain products boost your data?

From the bench to the paper

1

Simplifying experimental setups into an all-in-one compact design with the help of advanced, user-friendly acquisition and analysis software.

1

Simplifying experimental setups into an all-in-one compact design, including an advanced and user friendly acquisition and analysis software

See the BioCAM DupleX

2

Gaining a deeper understanding of neuronal networks using a sensitive technology that provides superior spatial and temporal resolution.

2

Getting a deeper understanding of neuronal networks using a sensitive technology providing a superior spatial and temporal resolution

See CorePlate™ technology

3

Obtaining clearer and more reliable statistics while requiring fewer experiments – all in a time-efficient manner.

3

Obtaining clearer and more reliable statistics while requiring less experiments - all in a time efficient manner

See latest publications

Resources

See our MEA neuro-imaging technology in action

Explore the capabilities of our neuron processors (also known as high density microelectrode arrays - HD-MEAs) and our software tools: take a look at these experimental data samples and download the free version of BrainWave.

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Latest News

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November 8, 2021

3Brain @ NECTAR 2021

3Brain is sponsoring and attending The 31st Annual Meeting of NECTAR & 16th INTR! Meet Dr. Sercan Deniz at our booth to see the BioCAM DupleX and get more info on how our HyperCAM Alpha will assist your research.

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October 28, 2021

New Publication: "All-Optical and Label-Free Stimulation of Action Potentials in Neurons and Cardiomyocytes by Plasmonic Porous Metamaterials"

Bruno et al, and researchers from the Istituto Italiano di Tecnologia have now introduced a new, all-optical, and nongenetic method to elicit activity with high spatio-temporal resolution while simultaneously recording network activity from cardiac and neuronal cultures.

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October 20, 2021

3Brain @ The International Workshop on Chronic Pain and Itch

3Brain are happy sponsors of The International Workshop on Chronic Pain and Itch, organized by Instituto de Neurociencias de Alicante  on 20-22nd Oct.

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Latest Publication

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Neuronal Cultures
A Monolayer System for the Efficient Generation of Motor Neuron Progenitors and Functional Motor Neurons from Human Pluripotent Stem Cells

Cutarelli A., Martínez-Rojas V.A., Tata A., Battistella I., Rossi D., Arosio D., Musio C., and Conti L.

MDPI (2021). DOI: https://doi.org/10.3390/cells10051127

Acute Brain Slices
Implementation of biohybrid olfactory bulb on a high-density CMOS-chip to reveal large-scale spatiotemporal circuit information

Hu X., Khanzada S., Klütsch D.,Calegari F., and Amin H.

ScienceDirect (2022). DOI: https://doi.org/10.1016/j.bios.2021.113834

Acute Retina
Transplanted pluripotent stem cell‐derived photoreceptor precursors elicit conventional and unusual light responses in mice with advanced retinal degeneration

Zerti D., Hilgen G., Dorgau B., Collin J., Ader M., Armstrong L., Sernagor E., and Lako M.

Stem Cells Journal (2021). DOI: https://doi.org/10.1002/stem.3365

Organoids
Human derived cortical excitatory neurospheroids showed spontaneous activity on micro electrodes array

Muzzi L. , Falappa M., Maccione A. , Di Lisa D. , Frega M. , and Martinoia S.

IEEE (2021) DOI: 10.1109/NER49283.2021.9441261

Latest Publications

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Neuronal Cultures
A Monolayer System for the Efficient Generation of Motor Neuron Progenitors and Functional Motor Neurons from Human Pluripotent Stem Cells

Cutarelli A., Martínez-Rojas V.A., Tata A., Battistella I., Rossi D., Arosio D., Musio C., and Conti L.

MDPI (2021). DOI: https://doi.org/10.3390/cells10051127

Acute Brain Slices
Implementation of biohybrid olfactory bulb on a high-density CMOS-chip to reveal large-scale spatiotemporal circuit information

Hu X., Khanzada S., Klütsch D.,Calegari F., and Amin H.

ScienceDirect (2022). DOI: https://doi.org/10.1016/j.bios.2021.113834

Acute Retina
Transplanted pluripotent stem cell‐derived photoreceptor precursors elicit conventional and unusual light responses in mice with advanced retinal degeneration

Zerti D., Hilgen G., Dorgau B., Collin J., Ader M., Armstrong L., Sernagor E., and Lako M.

Stem Cells Journal (2021). DOI: https://doi.org/10.1002/stem.3365

Organoids
Human derived cortical excitatory neurospheroids showed spontaneous activity on micro electrodes array

Muzzi L. , Falappa M., Maccione A. , Di Lisa D. , Frega M. , and Martinoia S.

IEEE (2021) DOI: 10.1109/NER49283.2021.9441261

Neuronal Cultures

Cutarelli A., Martínez-Rojas V.A., Tata A., Battistella I., Rossi D., Arosio D., Musio C., and Conti L.

MDPI (2021). DOI: https://doi.org/10.3390/cells10051127

Acute Brain Slices

Hu X., Khanzada S., Klütsch D.,Calegari F., and Amin H.

ScienceDirect (2022). DOI: https://doi.org/10.1016/j.bios.2021.113834

Acute Retina

Zerti D., Hilgen G., Dorgau B., Collin J., Ader M., Armstrong L., Sernagor E., and Lako M.

Stem Cells Journal (2021). DOI: https://doi.org/10.1002/stem.3365

Organoids

Muzzi L. , Falappa M., Maccione A. , Di Lisa D. , Frega M. , and Martinoia S.

IEEE (2021) DOI: 10.1109/NER49283.2021.9441261

Have any questions? Book a chat or email us, as our neuroscientist team is here to assist you.
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