Interfacing Neuronal Networks

Exploring the newest generation of HD-Microelectrode arrays: the CorePlate™

The 3Brain Massimo Grattarola Award
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3Brain wants to promote young neuroscientists at the beginning of their scientific journey with this opportunity to win a 10,000€ award!

We commit this Award in the name of Massimo Grattarola, one of the leading scientists and pioneer in the fields of bioelectronics and neuroengineering, who also laid the foundation for works that would have later merged into 3Brain.

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HyperCAM Alpha

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HyperCAM Alpha

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BioCAM DupleX

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BioCAM DupleX

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BioCAM DupleX

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BioCAM DupleX

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HyperCAM Alpha

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HyperCAM Alpha

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Single-Well
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Multiwell
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Software
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Accessories
The only fully bi-directional HD-MEA (microelectrode array) platform for 2D and 3D in vitro electrophysiology.

BioCAM DupleX

The only fully bi-directional HD-MEA platform for 2D and 3D in vitro electrophysiology.

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Our genuine HD-MEA (microelectrode array) platform with everything you need for in vitro neuronal physiology. - BioCAM X

BioCAM X

Our genuine HD-MEA platform with everything you need for in vitro neuronal physiology.

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Single-Well HD-MEAs

A varied selection of high-density MEAs to match your precise research needs.

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HyperCAM Alpha

The 6-well CorePlate™-powered platform designed for both cell culture and tissue preparations.

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CorePlate™ Multiwells

The CorePlate™ technology’s processing capabilities convert the multiwell plates into smart objects.

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BrainWave 4

The companion of our single-well HD-MEAs to visualize, record, and analyze cell activity in real-time.

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Single-Well Accessories

Expand the possibilities of the single-well BioCAM systems.

Discover more
Created with Sketch.
Single-Well
Created with Sketch.
Multi-Well
Created with Sketch.
Software
Created with Sketch.
Accessories
The only fully bi-directional HD-MEA platform for 2D and 3D in vitro electrophysiology.

BioCAM DupleX

The only fully bi-directional HD-MEA platform for 2D and 3D in-vitro electrophysiology.

Discover more

BioCAM X

Our genuine high-end HD-MEA platform with everything you need for in-vitro neuron physiology.

Discover more

Single-Well HD-MEAs

A varied selection of high-density MEAs to match your precise research needs.

Discover more

HyperCAM Alpha

The 6-well CorePlate™-powered platform designed for both cell culture and tissue preparations.

Discover more

CorePlate™ Multiwells

The CorePlate™ technology’s processing capabilities convert the multiwell plates into smart objects.

Discover more

BrainWave

The companion of our single-well HD-MEAs to visualize, record, and analyze cell activity in real-time.

Discover more

Single-Well Accessories

Expand the possibilities of the single-well BioCAM systems.

Discover more
Created with Sketch.
Single-Well
Created with Sketch.
Multi-Well
Created with Sketch.
Software
Created with Sketch.
Accessories
The only fully bi-directional HD-MEA platform for 2D and 3D in vitro electrophysiology.

BioCAM DupleX

The only fully bi-directional HD-MEA platform for 2D and 3D in-vitro electrophysiology.

Discover more

BioCAM X

Our genuine high-end HD-MEA platform with everything you need for in-vitro neuron physiology.

Discover more

Single-Well
HD-MEAs

A varied selection of high-density MEAs to match your precise research needs.

Discover more

HyperCAM Alpha

The 6-well CorePlate™-powered platform designed for both cell culture and tissue preparations.

Discover more

CorePlate™ Multiwells

The CorePlate™ technology’s processing capabilities convert the multiwell plates into smart objects.

Discover more

BrainWave

The companion of our single-well HD-MEAs to visualize, record, and analyze cell activity in real-time.

Discover more

Single-Well Accessories

Expand the possibilities of the single-well BioCAM systems.

Discover more
Our Mission

3Brain strives to provide researchers with breakthrough technology to improve the understanding of organs and their related illnesses.

3Brain strives to provide researchers with breakthrough technology to improve the understanding of organs and their related illnesses.

How can 3Brain products boost your data?

From the bench to the paper

1

Simplifying experimental setups into an all-in-one compact design, including an advanced and user friendly acquisition and analysis software

1

Simplifying experimental setups into an all-in-one compact design, including an advanced and user friendly acquisition and analysis software

See the BioCAM DupleX

2

Getting a deeper understanding of neuronal networks using a sensitive technology providing a superior spatial and temporal resolution

2

Getting a deeper understanding of neuronal networks using a sensitive technology providing a superior spatial and temporal resolution

See CorePlate™ technology

3

Obtaining clearer and more reliable statistics while requiring less experiments - all in a time efficient manner

3

Obtaining clearer and more reliable statistics while requiring less experiments - all in a time efficient manner

See latest publications

Resources

See our MEA neuro-imaging technology in action

Explore the capabilities of our neuron processors (also known as high density microelectrode arrays - HD-MEAs) and our software tools: take a look at these experimental data samples and download the free version of BrainWave.

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Latest News

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March 3, 2021

Collaboration with a:head bio AG

Today we'd like to announce our official collaboration with a:head bio AG on the development of 3Brain’s next generation microelectrode array (MEA): the CorePlate ™ technology.
With this collaboration we intend to improve the technology to allow for extraction of highly resolved electric signals from 3D biology in an automated, high-throughput work flow.

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January 29, 2021

Launching of the Neu-ChiP Project

Aston University has received €3.5m from the European Commission with many researchers including 3Brain AG, to show how neurons – the brain’s information processors – can be harnessed to supercharge computers’ machine learning abilities.

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January 27, 2021

The 3Brain - Massimo Grattarola Award

In memory of his pioneering work in Bioelectronics, we are honored to inaugurate the very first 3Brain - Massimo Grattarola Award on his birthday today! The Award aims to support young post doc neuroscientists into the start of their career.
Head into the page now to read the details and eligibility to apply for this research award and win 10,000€!

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Latest Publication

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Neuronal Cultures
Transfer Entropy Based Connectivity Estimation of Spontaneously Firing Hippocampal Cultures on Multi Electrode Arrays

Lama N., Hargreaves A.J., Stevens B., Mcginnity T.M.

International Joint Conference on Neural Networks (2019). DOI: 10.1109/IJCNN.2019.8851864

Acute Brain Slices
Neuronal Glutamatergic Network Electrically Wired with Silent But Activatable Gap Junctions

Ixmatlahua D. J., Vizcarra B., Gómez-Lira G., Romero-Maldonado I., Ortiz F., Rojas-Piloni G. and Gutiérrez R.

The Journal of Neuroscience (2020). DOI: https://doi.org/10.1523/JNEUROSCI.2590-19.2020

Acute Retina
Electrical Coupling of Heterotypic Ganglion Cells in the Mammalian Retina

Puller C., Duda S., Lotfi E., Arzhangnia Y., Block C. T., Ahlers M. T. and Greschner M.

Journal of Neuroscience (2020). DOI: https://doi.org/10.1523/JNEUROSCI.1374-19.2019

Organoids
Room temperature shipment does not affect the biological activity of pluripotent stem cell derived retinal organoids

Georgiou M., Chichagova V., Hilgen G., Dorgau B., Sernagor E., Armstrong L. and Lako M.

Plos One (2020). DOI: https://doi.org/10.1371/journal.pone.0233860

Latest Publications

View all  
Neuronal Cultures
Transfer Entropy Based Connectivity Estimation of Spontaneously Firing Hippocampal Cultures on Multi Electrode Arrays

Lama N., Hargreaves A.J., Stevens B., Mcginnity T.M.

International Joint Conference on Neural Networks (2019). DOI: 10.1109/IJCNN.2019.8851864

Acute Brain Slices
Neuronal Glutamatergic Network Electrically Wired with Silent But Activatable Gap Junctions

Ixmatlahua D. J., Vizcarra B., Gómez-Lira G., Romero-Maldonado I., Ortiz F., Rojas-Piloni G. and Gutiérrez R.

The Journal of Neuroscience (2020). DOI: https://doi.org/10.1523/JNEUROSCI.2590-19.2020

Acute Retina
Electrical Coupling of Heterotypic Ganglion Cells in the Mammalian Retina

Puller C., Duda S., Lotfi E., Arzhangnia Y., Block C. T., Ahlers M. T. and Greschner M.

Journal of Neuroscience (2020). DOI: https://doi.org/10.1523/JNEUROSCI.1374-19.2019

Organoids
Room temperature shipment does not affect the biological activity of pluripotent stem cell derived retinal organoids

Georgiou M., Chichagova V., Hilgen G., Dorgau B., Sernagor E., Armstrong L. and Lako M.

Plos One (2020). DOI: https://doi.org/10.1371/journal.pone.0233860

Neuronal Cultures

Lama N., Hargreaves A.J., Stevens B., Mcginnity T.M.

International Joint Conference on Neural Networks (2019). DOI: 10.1109/IJCNN.2019.8851864

Acute Brain Slices

Ixmatlahua D. J., Vizcarra B., Gómez-Lira G., Romero-Maldonado I., Ortiz F., Rojas-Piloni G. and Gutiérrez R.

The Journal of Neuroscience (2020). DOI: https://doi.org/10.1523/JNEUROSCI.2590-19.2020

Acute Retina

Puller C., Duda S., Lotfi E., Arzhangnia Y., Block C. T., Ahlers M. T. and Greschner M.

Journal of Neuroscience (2020). DOI: https://doi.org/10.1523/JNEUROSCI.1374-19.2019

Organoids

Georgiou M., Chichagova V., Hilgen G., Dorgau B., Sernagor E., Armstrong L. and Lako M.

Plos One (2020). DOI: https://doi.org/10.1371/journal.pone.0233860

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