Where the functional screening revolution begins

Name: BioCAM DupleX
Brand: 3Brain AG
Availability: InStock

Introducing a fully bi-directional microelectrode array platform for 2D and 3D in vitro imaging

Overview

In vitro electrophysiology reimagined

BioCAM DupleX is a state-of-the-art, high-resolution microelectrode array (also known as multielectrode array) platform for powerful in vitro functional imaging.

Its bidirectional electrodes make it possible to simultaneously record high-density electrophysiological data at 20 kHz and induce electrical neural network stimulation from any of the 4 096 microelectrodes.

This advanced platform works with both classical planar 2D cell culture as well as our innovative 3D HD-MEA technology.
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The BioCAM DupleX is compatible with our latest generation of Khíron chips, which feature 4 096 µNeedle electrodes to penetrate structured brain tissues and obtain signals from inside your biological models such as slices, organoids, or spheroids.

Our journey to perfection

1 product, 15 years of R&D

BioCAM DupleX is the result of 15 years of research and development, embodying our experience in bioengineering high-density microelectrode array (HD-MEA) devices, electrophysiology, data processing and biological models.
It is electrophysiology at its best.

BioCAM Idea
2004

BioCAM 4096
2012

BioCAM X
2015

BioCAM DupleX
2019

Electrophysiology in 3D

An ideal match: BioCAM DupleX and CorePlate™

The BioCAM DupleX is the first HD-MEA platform that is able to power 3D HD-MEAs (CorePlate^TM 1W-3D 38/60/90).

With CorePlate™ 1W-3D 38/60/90, the BioCAM DupleX can simultaneously record and stimulate from all 4 096 microelectrodes structured in a penetrating µNeedle grid.

These revolutionary µNeedle electrodes access information from inside all kinds of tissues – such as slices, organoids, spheroids and scaffolded 3D cultures – without damaging them. This makes the BioCAM DupleX the only platform for high-resolution in vitro 3D functional imaging.

Electrophysiology revolutionized

Complex electrophysiology setups, where the wiring of a single electrode to the amplifier can significantly change the noise level and impair the experiment, or where the interpretation of the signals coming from your setup is restricted to electrophysiological experts, are now a distant memory.

BioCAM DupleX makes setup as easy as possible by automating important settings and optimizing noise, thus making electrophysiology accessible to everyone. Complex electrophysiological traces are then converted into microscopy-like, easy-to-understand, fast-to-process functional images.

BioCAM DupleX makes setup as easy as possible by automating important settings and optimizing noise, thus making electrophysiology accessible to everyone. Complex electrophysiological traces are then converted into microscopy-like, easy-to-understand, fast-to-process functional images.

Sensing and actuation with 4 096 electrodes

Bidirectional platform

When paired with CorePlate™1W 38/60 or 1W-3D 38/60/90, the BioCAM DupleX can use any of the recording sites to release an electrical stimulus, thus making it a fully bidirectional platform.
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Coupled with BrainWave, our unique integrated software for recording, stimulation and real-time processing, BioCAM DupleX is the perfect solution for easily setting up complex experiments. Study functional connectivity, information processing or complex behaviors like learning and memory in neuronal networks – all without the need for external stimulating electrodes or third-party electronics.

Touch button and LED interface

Precision at your fingertips

After inserting CorePlate^™into the BioCAM DupleX, the motorized locking mechanism activates with a simple press of the lock button to enable precise contact and alignment. The system automatically recognizes the CorePlate^™ and is ready to acquire data.

After inserting a microelectrode array (HD-MEA) chip into the BioCAM DupleX, the motorized locking mechanism activates with a simple press of the lock button to enable precise contact and alignment. The system automatically recognizes the MEA chip and is ready to acquire data.

BioCAM Duplex - LED and touch button interface

A convenient set of LED lights shows when the BioCAM DupleX is powered on, whether CorePlate™ is locked in and when the system is recording.

A close-up view

Integrated reference

The BioCAM DupleX features an integrated reference electrode for CorePlate^™in orderto simplify the experimental procedure, reducing the risk of contamination, interference noise and accidental spills of media.

Under the case

REAL-TIME PROCESSING

Advanced FPGA control to denoise, filter and compress high-density data

MAGNETIC SURFACES

Magnetic surfaces are present on the front of the BioCAM DupleX for easy setup with other equipment, such as perfusion holders

TEMPERATURE CONTROL

Integrated heating and cooling system

Magnetic Surface - All the surfaces around the MEA chip are magnetic for easy setup with other equipment, such as perfusion holders

Real time processing - Advanced FPGA control to denoise, filter and compress high-density data.

Integrated Stimulator - 4 independently programmable current stimulator channels

Fast locking system - A motorized solution to reliably lock and unlock your microelectrode array (MEA) chips

BioCAM DupleX - discover more of all the features within this compact microelectrode array device

CURRENT STIMULATOR

2 independently programmable current stimulator channels

FAST LOCKING SYSTEM

A motorized solution to reliably lock and unlock CorePlate™

ROBUST EXTERNAL CASE

Crafted from aluminum to shield from electromagnetic and mechanical interference

An interactive version of this section is available on desktop PCs.