Explore new pathways in brain research and drug discovery
Human iPSC-derived neuronal culture
Neural progenitor derived cultures
Primary neuronal cell culture
Our single-well HD-MEAs and multiwell CorePlate™, based on high density microelectrode array technology, allow studying of the physiological and pathological functional activity of neuronal cultures. A versatile tool to investigate in detail the mechanisms of neuronal signal processing and to improve the quality and reliability of drug screenings or toxicological assays.
Advantages of using 3Brain technology on neuronal cultures:
Label-free functional monitoring of large networks with single-cell spiking activity resolution
Tracking of signal propagation among cells for functional connectivity studies
Kinetic functional assay to follow culture development over weeks and months
Improved statistical significance of the calculated network activity parameters
Click here to know how the technology works
Integrated spike detection and sorting algorithms
Different spike detection and sorting techniques are available in BrainWave software to extract and classify relevant cell activity
Automated statistical analysis of network parameters
The all-in-one BrainWave software will assist you in quickly obtaining results from your experimental session in a simple and intuitive way
Built-in stimulating capabilities
Investigate electrically evoked neural network responses by using the internal stimulator of the BioCAM systems and HyperCAM systems
Feel free to get in contact with our neuroscientists team for detailsContact Us
A collection of reviews from our customers
The BioCAM offers, for the first time, recordings at a scale that allow validation of models of neuronal population activity. This is a major step that will drive, in turn, the development of theories in neuroscience.
Dr. Matthias H. HennigComputational Neuroscience and NeuroinformaticsSee Link to Author’s Publication
We engineer a novel plasticity neuroelectronic platform using CMOS-MEA, nano-microtechnology and computational tools to decipher the molecular and functional plasticity simultaneously in a large-scale circuit/network in health and disease.
Dr. Hayder AminBiohybrid Neuroelectronics LabSee Link to Author’s Publication
I have conducted a wide range of brain slices as well as neuron culture experiments in 3Brain's HD MEA system. Their technology is beyond expectation in terms of sensitivity, durability, and high STN ratio.
Prof. Kim SangSeongHanyang University College of Pharmacy
Our laboratory works on brain experimental recordings and modeling on multiple scales, from molecular/cellular to whole brain in animals and humans. The use of BioCAM X integrates perfectly into the workflow as it allows a unique set of measurements on distributed network activities.
Prof. Egidio D’AngeloUniversity of Pavia See Link to Author’s Publication
The BioCAM has revolutionized the way we look at population activity in the retina. With its overall large size and spatial resolution, it allows us to study population behaviour at unprecedented spatial and temporal detail.
Prof. Evelyne SernagorRetinal NeuroscienceSee Link to Author’s Publication
It is a pleasure to work with the 3Brain team, they are both highly skilled experts and friendly.
Dr. Fred Jordan, Co-CEOFinalSpark
The Muotri lab uses 3Brain high-resolution multi electrode arrays to understand how human neural networks are formed during development, and become altered in several neurological conditions.
Prof. Alysson Muotri
3Brain has impressed me with the quality of its products. The BioCAM DupleX has been the perfect platform to aid our drug discovery efforts at Xenon, and the personal one-on-one assistance continues to exceed my expectations.
Dr. Ryley ParrishXenon Pharmaceuticals Inc.
The HD MEAs allow us to perform accurate cardiotoxicity assessments on hiPS cardiomyocytes by applying a novel laser technology for recording high-quality action potentials from thousands of cardiac cells simultaneously.
Location to specific products and samples within 3Brain's resources
APS Physics (2022). DOI: 10.1103/PhysRevE.105.044406
Cells (2021). DOI: 10.3390/cells10051127
International Joint Conference on Neural Networks (2019). DOI: 10.1109/IJCNN.2019.8851864