Ex-vivo acute retinal explant

Shed light on retinal activity in vitro. Record responses to light stimuli and generate retinal ganglion cells (RGCs) mosaics.

Models

  • Whole mount retina explants

  • Primate and non-primate retina tissues

Advantages

Explanted retinas from different animal models (e.g. murine, salamander, primates, etc.) can be studied up-close on our single-well or multi-well CorePlate™. With the largest active microelectrode area on the market (up to 25mm²), they are optimized for recording single cell activity over large tissue samples.

Advantages of 3Brain technology with explanted retinas are:

  • Entire retinal ganglion cell network mapping at single-cell resolution.

  • Record light-induced retinal network activity by combining our BioCAM platform with light-stimulation devices.

  • Combine with optogenetic stimulation tools for spatiotemporally precise excitation/inhibition of cells

  • Single cell visualization of signal propagation

Click here to know how the technology works.  

Tools & Features

Different spike detection and sorting techniques are available in BrainWave software to extract and classify relevant cell activity - 3Brain
  • Integrated spike/LFP detection and sorting al

    Run sophisticated analyses like spike-sorting to evaluate your results for statistical significance with BrainWave, our most elaborated retinal electrophysiology data analysis software.

the HDF5 file format of BrainWave  is fully compatibile with third-party softwares - 3Brain
  • Full compatibility with third-party softwares

    HDF5 file format raw data readable with Python, Igor Pro, Matlab…Run your custom home made analysis routines.

3Brain's BrainWave software also synchronizes a light stimulator with our BioCAM systems - 3Brain
  • Synchronize light stimulator with BioCAM systems

    Run sophisticated analyses like spike-sorting to evaluate your results for statistical significance with

Ability to design your experimental session through the BrainWave software - 3Brain
  • Design your experimental session

    The BrainWave  intuitive graphical user interface gives the user full control of the experimental designto rapidly obtain results from an experimental session.

Feel free to get in contact with our neuroscientists team for details

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Resources

3Brain's 24-well HD-MEA, HyperCAM Delta.
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