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Our high-density microelectrode array (HD-MEA), also known as multielectrode array, features 4,096 low-noise microelectrodes that allow for simultaneous electrophysiological recording.
Investigating cellular networks requires time, expertise and effort to obtain the performance necessary to validate research hypotheses. With 3Brain as your technology partner, you can easily capture every cell signal in high resolution.
Our powerful CMOS MEA (microelectrode array / multielectrode array) system collects high-density electrophysiological data from preparations made of brain slices, neuronal tissue, human-derived stem cells,brain organoids, retinal tissue and cardiac cultures and tissues.
Different HD-MEA chip models for our microelectrode arrays are available to match your experimental needs in terms of resolution, field of view and stimulation capabilities.
Electrodes are coated with platinum to provide a stable and fully biocompatible surface. The quality of the recording is ensured by the outstanding signal-to-noise ratio, as you can see from our video samples gallery.
The Accura microelectrode array features 4,096 recording electrodes arranged in a 3.8 mm x 3.8 mmarea, a perfect compromise for both cultures and brain tissues. Compared to previous chipset families, Accura achieves an improved signal-to-noise ratio by offering a recording mode where a subset electrode area can be accessed for ultra-low noise performance.
Moreover, every single recording electrode can also be used to release an electrical signal to your sample. The Accura HD-MEA Accura provides a 3.8 mm x 3.8 mm grid of 4,096 electrodes for spatially accurate electrical stimulation at a cellular resolution.
Each microelectrode is 21 µm x 21 µm, with a 60 µm pitch. The internal diameter of the reservoir is 25 mm, with a height of 7 mm.
The Accura HD-MEA is based on the Khíron (Gen 3) chipset family and is compatible with BioCAM DupleX only.
Thanks to the AziGrip4™ CELL+ surface functionalization technology developed incollaboration with SuSoS AG, Accura microelectrode arrays can be provided in a pre-coated, sterile and ready-to-use version for cell cultures. By removing the need for manual functional coating and sterilization, both preparation time and variability in cell cultures between MEAs are reduced. Furthermore, it provides a homogeneous and reliable adhesion of cells to substrate, thus increasing the success rate of your experiments.
At a glance
Accura micreoelectrode array features 4096 recording electrodes arranged in a 3.8 mm x 3.8 mm area, a perfect compromise for both cultures and brain tissues. Compared to the previous chipset families, Accura achieves an improved signal to noise ratio by offering a recording mode where a subset electrode area can be accessed for ultra-low noise performances.
Moreover, every single recording electrode can also be used to release an electrical signal to your sample. In this way HD-MEA Accura provides a 3.8 mm x 3.8 mm grid of 4096 electrodes for spatially accurate electrical stimulation at a cellular resolution.
Each microelectrode is 21 µm x 21 µm, with a 60 µm pitch. The internal diameter of the reservoir is 25 mm, with a height of 7 mm.
HD-MEA Accura is from Khíron (Gen 3) chipset family and can be used with BioCAM DupleX only.
Thanks to the AziGrip4™ CELL+ surface functionalization technology developed in collaboration with SuSoS AG, Accura microelectrode arrays can be provided in a pre-coated, sterile and ready-to-use version for cell cultures. By removing the need for manual functional coating and sterilization, both preparation time and variability in cell cultures between MEAs are reduced. Furthermore it provides a homogeneous and reliable adhesion of your cells to the substrate, thus increasing the success rate of your experiments.
At a glance
Accura micreoelectrode array features 4096 recording electrodes arranged in a 3.8 mm x 3.8 mm area, a perfect compromise for both cultures and brain tissues. Compared to the previous chipset families, Accura achieves an improved signal to noise ratio by offering a recording mode where a subset electrode area can be accessed for ultra-low noise performances.
Moreover, every single recording electrode can also be used to release an electrical signal to your sample. In this way HD-MEA Accura provides a 3.8 mm x 3.8 mm grid of 4096 electrodes for spatially accurate electrical stimulation at a cellular resolution.
Each microelectrode is 21 µm x 21 µm, with a 60 µm pitch. The internal diameter of the reservoir is 25 mm, with a height of 7 mm.
HD-MEA Accura is from Khíron (Gen 3) chipset family and can be used with BioCAM DupleX only.
Thanks to the AziGrip4™ CELL+ surface functionalization technology developed in collaboration with SuSoS AG, Accura microelectrode arrays can be provided in a pre-coated, sterile and ready-to-use version for cell cultures. By removing the need for manual functional coating and sterilization, both preparation time and variability in cell cultures between MEAs are reduced. Furthermore it provides a homogeneous and reliable adhesion of your cells to the substrate, thus increasing the success rate of your experiments.
At a glance
Arenahas the same microelectrode recording array as the Prime model (4,096 electrodes in a 2.67 mm x 2.67 mm area), but offers a larger surrounding flat area (~6 mm x 6 mm), which is ideal for positioning large tissues while guaranteeing optimal coupling with the microelectrode array.
Each microelectrode is 21 µm x 21 µm, with a pitch of 42 µm. The internal diameterof the reservoir is 25 mm, with a height of 7 mm.
The Arena HD-MEA is based on the Artemis (Gen2) chipset family and can be used with BioCAM X and BioCAM DupleX.
At a glance
Arena has the same microelectrode recording array as the Prime model (4,096 electrodes in a 2.67 mm x 2.67 mm area), but offers a larger surrounding flat area (~6 mm x 6 mm), which is ideal for positioning large tissues while guaranteeing optimal coupling with the microelectrode array.
Each microelectrode is 21 µm x 21 µm, with a 42 µm pitch. The internal diameter of the reservoir is 25 mm, with a height of 7 mm.
HD-MEA Arena is from Artemis (Gen2) chipset family and can be used with BioCAM X and BioCAM DupleX.
At a glance
Arena has the same microelectrode recording array as the Prime model (4,096 electrodes in a 2.67 mm x 2.67 mm area), but offers a larger surrounding flat area (~6 mm x 6 mm), which is ideal for positioning large tissues while guaranteeing optimal coupling with the microelectrode array.
Each microelectrode is 21 µm x 21 µm, with a 42 µm pitch. The internal diameter of the reservoir is 25 mm, with a height of 7 mm.
HD-MEA Arena is from Artemis (Gen2) chipset family and can be used with BioCAM X and BioCAM DupleX.
At a glance
The Stimulo HD-MEA features a large sensing area (5.12 mm x 5.12 mm) with an increased electrode pitch of 81 µm. This makes it possible to record electrophysiological activity from large portions of neuronal tissue while maintaining a high spatial resolution.
The Stimulo model also features a secondary array for stimulation with 16 microelectrodes, arranged in a 4 x 4 uniform grid, that are interspersed between the recording electrodes.
The electrode size for both recording and stimulating electrodes is 21 µm x 21 µm. The internal diameter of the reservoir is 25 mm, with a height of 7 mm.
HD-MEAStimulo is based on the Artemis (Gen 2) chipset family and can be used with BioCAM X and BioCAM DupleX.
At a glance
The Stimulo HD-MEA features a large sensing area (5.12 mm x 5.12 mm) with an increased electrode pitch of 81 µm pitch. This makes it possible to record electrophysiological activity from large portions of neuronal tissue while maintaining a high spatial resolution.
Moreover, the Stimulo model features a secondary array for stimulation with 16 microelectrodes, arranged in a 4 x 4 uniform grid, that are interspersed between the recording electrodes.
The electrode size for both recording and stimulating electrodes is 21 µm x 21 µm. The internal diameter of the reservoir is 25 mm, with a height of 7 mm.
HD-MEA Stimulo is from Artemis (Gen 2) chipset family and can be used with BioCAM X and BioCAM Duplex.
At a glance
The Stimulo HD-MEA features a large sensing area (5.12 mm x 5.12 mm) with an increased electrode pitch of 81 µm pitch. This makes it possible to record electrophysiological activity from large portions of neuronal tissue while maintaining a high spatial resolution.
Moreover, the Stimulo model features a secondary array for stimulation with 16 microelectrodes, arranged in a 4 x 4 uniform grid, that are interspersed between the recording electrodes.
The electrode size for both recording and stimulating electrodes is 21 µm x 21 µm. The internal diameter of the reservoir is 25 mm, with a height of 7 mm.
HD-MEA Stimulo is from Artemis (Gen 2) chipset family and can be used with BioCAM X and BioCAM Duplex.
At a glance
Primeis a high-density microelectrode array (HD-MEA) integrating 4,096 recording electrodes on a small and compact area of 2.67 mm x 2.67 mm, centered on a flat area of ~3 mm x 3 mm. This arrangement is ideal in reducing the number of seeded cells.
Each microelectrode is 21 µm x 21 µm, with a pitch of 42 µm. The internal diameter of the reservoir is 25 mm, with a height of 7 mm.
The Prime HD-MEAis based on the Apollo (Gen 1) chipset family and can be used with BioCAM X and BioCAM DupleX.
At a glance
Prime is a high-density microelectrode array integrating 4,096 recording electrodes on a small and compact area of 2.67 mm x 2.67 mm, centered on a flat area of ~3 mm x 3 mm. This arrangement is ideal in reducing the number of seeded cells.
Each microelectrode is 21 µm x 21 µm, with a 42 µm pitch. The internal diameter of the reservoir is 25 mm, with a height of 7 mm.
HD-MEA Prime is from Apollo (Gen 1) chipset family and can be used with BioCAM X and BioCAM DupleX.
At a glance
Prime is a high-density microelectrode array integrating 4,096 recording electrodes on a small and compact area of 2.67 mm x 2.67 mm, centered on a flat area of ~3 mm x 3 mm. This arrangement is ideal in reducing the number of seeded cells.
Each microelectrode is 21 µm x 21 µm, with a 42 µm pitch. The internal diameter of the reservoir is 25 mm, with a height of 7 mm.
HD-MEA Prime is from Apollo (Gen 1) chipset family and can be used with BioCAM X and BioCAM DupleX.
At a glance
Main Electrode Array
Mode of operation
Recording and stimulation
# of electrodes
4,096 arranged in a 64 x 64 grid
Electrodes' area size (active area)
3.84 mm x 3.84 mm
Electrode size
21 µm x 21 µm
Electrode pitch
60 µm
Working Area
Flat area size
~6 mm x 6 mm
Main Electrode Array
Mode of operation
Recording
# of electrodes
4,096 arranged in a 64 x 64 grid
Electrodes' area size (active area)
2.67 mm x 2.67 mm
Electrode size
21 µm x 21 µm
Electrode pitch
42 µm
Working Area
Flat area size
~6 mm x 6 mm
Main Electrode Array
Mode of operation
Recording
# of electrodes
4,096 arranged in a 64 x 64 grid
Electrodes' area size (active area)
5.12 mm x 5.12 mm
Electrode size
21 µm x 21 µm
Electrode pitch
81 µm
Second Electrode Array
Mode of operation
Stimulation
# of electrodes
16 arranged in a 4 x 4 grid and uniformly interspersed between main array
Electrodes' area size (active area)
3.96 mm x 3.96 mm
Electrode size
21 µm x 21 µm
Electrode pitch
1.3 mm
Working Area
flat area size
~6 mm x 6 mm
Main Electrode Array
Mode of operation
Recording
# of electrodes
4,096 arranged in a 64 x 64 grid
Electrodes' area size (active area)
2.67 mm x 2.67 mm
Electrode size
21 µm x 21 µm
Electrode pitch
42 µm
Working Area
Flat area size
~3 mm x 3 mm
