CorePlate™ 1W: High-density microelectrode arrays with large sensing areas

Our high-density microelectrode array (HD-MEA), also known as multielectrode array, features 4,096 low-noise microelectrodes that allow for simultaneous electrophysiological recording.

3Brain's Single-well high-density microelectrode arrays features 4,096 low-noise microelectrodes that allow for simultaneous electrophysiological recording.

Overview

The perfect tool for your brain research

Investigating cellular networks requires time, expertise and effort to obtain the performance necessary to validate research hypotheses. With 3Brain as your technology partner, you can easily capture every cell signal in high resolution.
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Our powerful HD-MEA (microelectrode array / multielectrode array) system collects high-density electrophysiological data from preparations made of brain slices, neuronal tissue, human-derived stem cells, brain organoids, retinal tissue and cardiac cultures and tissues.

Different HD-MEA chip models for our microelectrode arrays are available to match your experimental needs in terms of resolution, field of view and stimulation capabilities.
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Electrodes are coated with platinum to provide a stable and fully biocompatible surface. The quality of the recording is ensured by the outstanding signal-to-noise ratio, as you can see from our CorePlate™ Example Recordings.

Recording and stimulating capabilities for all your applications

CorePlate™ 1W 38/60

The CorePlate™1W 38/60 microelectrode array features 4,096 recording electrodes arranged in a 3.8 x 3.8 mm² area, a perfect compromise for both cultures and brain tissues. Compared to previous versions, CorePlate™1W 38/60 achieves an improved signal-to-noise ratio by offering a recording mode where a subset electrode area can be accessed for ultra-low noise performance.

Moreover, every single recording electrode is bidirectional and can be used to release an electrical signal to your sample. The CorePlate™1W 38/60 provides a 3.8 x 3.8 mm² grid of 4,096 electrodes for spatially accurate electrical stimulation at a cellular resolution.

Each microelectrode is 21 x 21 µm², with a 60 µm pitch. The internal diameter of the reservoir is 25 mm, with a height of 7 mm.

The CorePlate™1W 38/60 is compatible with the BioCAM DupleX only.

At a glance

More space to accommodate large tissues

CorePlate™ 1W 27/42L

CorePlate™ 1W 27/42L has the same microelectrode recording array as the CorePlate™ 1W 27/42 (4,096 electrodes in a 2.7 x 2.7 mm² area), but offers a larger surrounding flat area (~6 x 6 mm²), which is ideal for positioning large tissues while guaranteeing optimal coupling with the microelectrode array.

Each microelectrode is 21 x 21 µm², with a pitch of 42 µm. The internal diameter of the reservoir is 25 mm, with a height of 7 mm.
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The CorePlate™ 1W 27/42L is compatible with the BioCAM X and BioCAM DupleX.

At a glance

Ideal for cell cultures

CorePlate™ 1W 27/42

CorePlate™ 1W 27/42 is a high-density microelectrode array (HD-MEA) integrating 4,096 recording electrodes on a small and compact area of 2.7 x 2.7 mm², centered on a flat area of ~3 x 3 mm². This arrangement is ideal in reducing the number of seeded cells.
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Each microelectrode is 21 x 21 µm², with a pitch of 42 µm. The internal diameter of the reservoir is 25 mm, with a height of 7 mm.
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The CorePlate™ 1W 27/42 is compatible with the BioCAM X and BioCAM DupleX.

At a glance

Largest sensing area and stimulation capabilities

CorePlate™ 1W 51/81

The CorePlate™ 1W 51/81 features a large sensing area (5.1 x 5.1 mm²) with an increased electrode pitch of 81 µm. This makes it possible to record electrophysiological activity from large portions of neuronal tissue while maintaining a high spatial resolution.

The CorePlate™ 1W 51/81 also features a secondary array for stimulation with 16 microelectrodes, arranged in a 4 x 4 uniform grid, that are interspersed between the recording electrodes.

The electrode size for both recording and stimulating electrodes is 21 x 21 µm². The internal diameter of the reservoir is 25 mm, with a height of 7 mm.
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CorePlate™ 1W 51/81 is compatible with both the BioCAM X and BioCAM DupleX. CorePlate™ 1W 51/81 supports seamless recording with the BioCAM DupleX. When paired with the BioCAM X, both recording and stimulation are fully enabled

At a glance