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Our high-density microelectrode array (HD-MEA), also known as multielectrode array, features 4,096 low-noise microelectrodes that allow for simultaneous electrophysiological recording.
Investigating cellular networks often requires time, expertise and efforts to obtain the performance necessary to validate research hypotheses. With 3Brain as your technology partner, you will be able to easily capture every cell signal in high resolution.
Our powerful multielectrode array (HD-MEA) collects high-density electrophysiological data from preparations made of brain slices, neuronal tissue, human-derived stem cells, brain organoids, retinal tissue and cardiac cultures/tissues.
Different HD-MEA chip models for our microelectrode arrays are available to match your experimental needs in terms of resolution, field of view and stimulation capabilities.
Electrodes are coated with platinum to provide a stable and fully biocompatible surface. The quality of the recording is ensured by the outstanding signal-to-noise ratio, as you can see from our video samples gallery.
Accura micreoelectrode array features 4096 recording electrodes arranged in a 3.8mm x 3.8 mm area, a perfect compromise for both cultures and brain tissues. Compared to the previous chipset families, Accura achieves an improved signal to noise ratio by offering a recording mode where a subset electrode area can be accessed for ultra-low noise performances.
Moreover, every single recording electrode can also be used to release an electrical signal to your sample. In this way HD-MEA Accura provides a 3.8mm x 3.8mm grid of 4096 electrodes for spatially accurate electrical stimulation at a cellular resolution.
Each microelectrode is 21µm x 21µm, with a 60 µm pitch. The internal diameter of the reservoir is 25mm, with a height of 7mm.
HD-MEA Accura is from Khíron (Gen 3) chipset family and can be used with BioCAM DupleX only.
At a glance
Arena has the same microelectrode recording array as the Prime model (4,096 electrodes in a 2.67mm x 2.67mm area), but offers a larger surrounding flat area (~6mm x 6mm), which is ideal for positioning large tissues while guaranteeing optimal coupling with the microelectrode array.
Each microelectrode is 21µm x 21µm, with a 42 µm pitch. The internal diameter of the reservoir is 25mm, with a height of 7mm.
HD-MEA Arena is from Artemis (Gen2) chipset family and can be used with BioCAM X and BioCAM DupleX.
At a glance
The Stimulo HD-MEA features a large sensing area (5.12mm x 5.12mm) with an increased electrode pitch of 81µm pitch. This makes it possible to record electrophysiological activity from large portions of neuronal tissue while maintaining a high spatial resolution.
Moreover, the Stimulo model features a secondary array for stimulation with 16 microelectrodes, arranged in a 4 x 4 uniform grid, that are interspersed between the recording electrodes.
The electrode size for both recording and stimulating electrodes is 21µm x 21µm. The internal diameter of the reservoir is 25mm, with a height of 7mm.
HD-MEA Stimulo is from Artemis (Gen 2) chipset family and can be used with BioCAM X and BioCAM Duplex.
At a glance
Prime is a high-density microelectrode array integrating 4,096 recording electrodes on a small and compact area of 2.67mm x 2.67mm, centered on a flat area of ~3mm x 3mm. This arrangement is ideal in reducing the number of seeded cells.
Each microelectrode is 21µm x 21µm, with a 42µm pitch. The internal diameter of the reservoir is 25mm, with a height of 7mm.
HD-MEA Prime is from Apollo (Gen 1) chipset family and can be used with BioCAM X and BioCAM DupleX.
At a glance
Main Electrode Array
Mode of operation
Recording and stimulation
# of electrodes
4096 arranged in a 64 x 64 grid
Electrodes' area size (active area)
3.84mm x 3.84mm
Electrode size
21µm x 21µm
Electrode pitch
60µm
Working Area
Flat area size
~6mm x 6mm
Main Electrode Array
Mode of operation
Recording
# of electrodes
4096 arranged in a 64 x 64 grid
Electrodes' area size (active area)
2.67mm x 2.67mm
Electrode size
21µm x 21µm
Electrode pitch
42µm
Working Area
Flat area size
~6mm x 6mm
Main Electrode Array
Mode of operation
Recording
# of electrodes
4096 arranged in a 64 x 64 grid
Electrodes' area size (active area)
5.12mm x 5.12mm
Electrode size
21µm x 21µm
Electrode pitch
81µm
Second Electrode Array
Mode of operation
Stimulation
# of electrodes
16 arranged in a 4 x 4 grid and uniformly interspersed between main array
Electrodes' area size (active area)
3.96mm x 3.96mm
Electrode size
21µm x 21µm
Electrode pitch
1.3mm
Working Area
flat area size
~6mm x 6mm
Main Electrode Array
Mode of operation
Recording
# of electrodes
4096 arranged in a 64 x 64 grid
Electrodes' area size (active area)
2.67mm x 2.67mm
Electrode size
21µm x 21µm
Electrode pitch
42µm
Working Area
Flat area size
~3mm x 3mm
